Vp, Discovery and Platform Biology

Vor 6 Tagen


Basel, Schweiz Monte Rosa Therapeutics, Inc Vollzeit

Overview:
Monte Rosa Therapeutics is seeking a Vice President of Discovery and Platform Biology. This person will be responsible for implementing the company’s efforts to identify molecular glue degraders to high value targets and expanding the toolbox of enabling platform technologies. The ideal candiate has a high level of experience directing innovative approaches in the area of targeted protein degradation. A proven track record of leading large multi-disciplinary teams and extensive experience in early drug discovery, including lead discovery, biochemistry, structural biology, and ligase biology.

**Responsibilities**:
Sets scientific direction for the the Discovery and Platform Technologies team to achieve department goals and contributes to managing priorities of the company’s portfolio.

Designs and executes early discovery and platform development strategies to identify leads to targets in oncology, immunology and other therapeutic areas, coordinates these efforts with other functional areas, project managers, and external collaborators

Drives the discovery, development, and implementation of new technological approaches and capabilities to enable discovery of molecular glue degraders to novel neosubstrates.

Sets the vision & establishes and manages workflows that enable productivity, creativity, and integrates new technologies to ensure that Monte Rosa operates at the leading edge of drug discovery.

Creates and implement project plans, and coordinate workflow and logistics to meet corporate goals and milestones.

Oversees selection and strategy of CRO’s while leading build out of internal capabilities

Provides coaching, leadership, and management to facilitate effective solutions for projects and the functional areas of lead discovery, biochemistry, structural biology, and ligase biology.

Maintains high external visibility. Actively participates in professional conferences. Publishes scientific findings in peer-reviewed journals and other forums to promote Monte Rosa and its science.

Qualifications:

- Ph.D. in biochemistry, biology or structural biology with an emphasis on lead discovery and early drug discovery
- 15+ year experience in drug discovery/pharmaceutical research.
- Proven track record in the field of targeted protein degradation and the discovery of small molecule degraders.
- Effective communication skills and ability with leadership skills with experience in effectively guide and manage discovery teams to achieve department goals with internal colleagues and external collaborators.
- Proven track record of scientific achievement (publications, patents, presentations).
- Excellent oral, written, and interpersonal skills.
- Embodies MRTxvalues; exhibits high degree of integrity and professionalism when interacting with consultants, external vendors and contract research organizations.
- Strong organizational skills; ability to prioritize and multitask in order to deliver high quality work product on agreed-upon timelines and budget.
- Experience managing external contracts and tracking budgets.



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