Molecular Cell Biology Research Assistant 80-100%

Vor 4 Tagen


Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel Vollzeit

The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated **Research Assistant** to join the Retinal Organoid Platform.

IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded.

The Human Organoid Platform uses human retinal organoids in combination with genome engineering to create disease models and test novel gene-therapy approaches for human blinding disorders. The human organoid platform is continuously developing new methodologies to improve the culture and analysis of retinal organoids, as well as implementing new read-outs for ocular disease phenotypes in retinal organoids. Furthermore, we aim to develop new cell culture models of ocular tissues to develop new research tools for our collaborators.

**Your responsibilities**
- In vitro culture of human pluripotent stem cells
- Genome engineering of pluripotent stem cells by CRISPR/Cas9, and characterization of mutant organoids
- Differentiation of pluripotent stem cells to various cell types and tissues of the human eye and combining them to develop novel research tools
- Vector construction and molecular cloning
- Analysis of retinal organoids and various ocular cell types by histology, microscopy and molecular biology techniques
- Involvement in lab management and organization
- Close collaboration with group members and IOB groups

**Requirements**:

- Biologielaborant/in (or equivalent education) with several years of work experience or Bachelor’s/Master’s Degree (or equivalent) in molecular biology or related field
- Excellent aseptic cell culture technique
- Independence in the planning, conductance, analysis and troubleshooting of standard molecular biology experiments
- Willingness to work with lentivirus, human tissue and standard hazardous laboratory compounds
- Enthusiasm to establish and optimize new protocols and techniques
- Highly organized, detail-oriented and skilled with computers
- Good written and verbal communications skills in English
- Some work during weekends and public holidays

**We offer**
- Highly competitive conditions in a dynamic and international research community in Basel
- IOB is an equal-opportunity employer with family-friendly work policies

**Application / Contact**

In your cover letter please mention which yet missing cell type you would like to integrate into retinal organoids.

IOB - Institute of Molecular and Clinical Ophthalmology Basel
Sandro Crameri
Head of Human Resources
: +41 79 511 26 54



  • Basel, Basel-Stadt, Schweiz Universität Basel Vollzeit

    The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated Research Assistant to join the Human Retinal Circuits Group at IOB, led by Botond Roska.The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is a research institute combining basic and clinical research. Its mission is to drive innovations in...


  • Basel, Basel-Stadt, Schweiz Universität Basel Vollzeit

    The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated Research Assistant to join the Single-Cell Genomics Platform.IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place...


  • Basel, Schweiz Institute of Molecular Cancer Research Vollzeit

    Institute of Molecular Cancer Research_ **Postdoctoral Researcher** **Your responsibilities**: Maintaining genome stability is crucial for all living cells and organisms. To ensure the fidelity of genome duplication, a complex series of processes has been evolved, known as DNA damage response (DDR), to cope with chromosomal lesions by activating various...


  • Basel, Schweiz Universität Basel Vollzeit

    The Biozentrum of the University of Basel is one of the leading Life Sciences Institutes in the world. It accommodates 32 research groups and 500 employees investigating how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birthplace of many fundamental discoveries in biology and...


  • Basel, Basel-Stadt, Schweiz Universität Basel Vollzeit

    The Biozentrum of the University of Basel is one of the leading Life Sciences Institutes in the world. It accommodates 32 research groups and 500 employees investigating how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birthplace of many fundamental discoveries in biology and...


  • Basel, Schweiz Universität Basel Vollzeit

    The Swiss Tropical and Public Health Institute (Swiss TPH) is a world-leading institute in global health with a particular focus on low - and middle-income countries. Associated with the University of Basel, Swiss TPH combines research, education and services at local, national and international levels. 900 people from 80 nations work at Swiss TPH focusing...


  • Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel Vollzeit

    The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a motivated and skilled **Research Assistant/Lab Manager** - as maternity cover for nine months - to join the Translational Group working in close collaboration with the IOB Retinal Organoid Platform. IOB is a research institute combining basic and clinical research. Its mission is...


  • Basel, Schweiz Universität Basel Vollzeit

    How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world's leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and...


  • Basel, Basel-Stadt, Schweiz Universität Basel Vollzeit

    How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world's leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and...

  • Research Associate

    vor 3 Wochen


    Basel, Schweiz Coopers Group AG Vollzeit

    Research Associate - Cancer Cell Therapy For our international client in Basel, we are looking for a Research Associate in Cancer Cell Therapy. **Responsibilities** - Development of pharmacodynamic (PD) assays that will provide robust and accurate measurements of drug effects in cell lines and in samples of mouse models. - Implementation of biomarker...


  • Basel, Schweiz Universität Basel Vollzeit

    How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world's leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and...


  • Basel, Schweiz Universität Basel Vollzeit

    How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world's leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and...


  • Basel, Basel-Stadt, Schweiz Universität Basel Vollzeit

    How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world's leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and...


  • Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel Vollzeit

    The Institute of Molecular and Clinical Ophthalmology Basel (IOB) seeks a qualified and highly motivated **Research Assistant **with experience in protein production. IOB is a new research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its related diseases and to develop new therapies for...


  • Basel, Schweiz Universität Basel Vollzeit

    The Jenal Lab at the Biozentrum is seeking a highly motivated and skilled laboratory technician with expertise in cell culture to join our team. This 80%-100% position offers an exciting opportunity to contribute to cutting-edge research in lung infections and antibiotic discovery. **About the Biozentrum** How does life emerge from molecules and cells? This...

  • Research Associate

    vor 3 Wochen


    Basel, Schweiz CTC Resourcing Solutions Vollzeit

    **Research Associate - Cancer Cell Targeted Therapy 5346** Our client is a pioneer in Drug Discovery and Development and one of the frontrunners in Personalised Healthcare. As the world's largest R&D spender in the pharmaceutical and diagnostics domain, they work in a vast number of drug discovery & therapeutic areas and are highly recognized...


  • Basel, Schweiz The Biozentrum, University of Basel Vollzeit

    Your position Lung Organoid Culture Management (50%): Maintain and manage lung organoid cultures (transwell model). Cell Culture Lab Organization (25%): Oversee the organization and maintenance of the cell culture laboratory. Experimental Support (25%): Perform in vitro experiments and imaging (histology, immunocytochemistry) and assist PhD...


  • Basel BS, Schweiz Universität Basel Vollzeit

    Technician - Cell Culture & Human Tissues - Jenal lab 80-100% Starting September 1, 2024 or by agreement The Jenal Lab at the Biozentrum is seeking a highly motivated and skilled laboratory technician with expertise in cell culture to join our team. This 80%-100% position offers an exciting opportunity to contribute to cutting-edge research in lung...


  • Basel, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international medical partner, F. Hoffmann-La Roche Ltd. in Kaiseraugst, we are looking for a qualified and motivated **Research Associate in NGS and Genomics 80-100%** for a temporary contract of 18 month. We are seeking a highly motivated and creative scientist to join the RNA Technologies Group in the Nucleic Acid based Medicine...


  • Basel, Basel-Stadt, Schweiz Department of Biosystems Science and Engineering Vollzeit

    Job Opportunity Join our team to work on cutting-edge projects that combine basic and translational research aimed at developing innovative principles inspired by synthetic biology. By strategically programming human cell behavior, we are paving the way for future breakthroughs in biomedical applications. Your tasks may involve creating new biosensors,...