Medical Director

vor 2 Wochen

Basel, Schweiz Novartis Vollzeit

385923BR

**Medical Director / Rheumatology, Autoimmune Translational Medicine**:
Switzerland

**About the role**

30 million That is the estimated number of patients worldwide suffering from inflammatory arthritis. Join Novartis to help find the right drugs that transform and improve patients' lives all around the world.

Your responsibilities will include:

- Medical / scientific contributor and leader of complex global cross-functional teams. Our successful drug discovery and development environment has close collaboration across Research, Clinical Research and Development.
- Major initiator of the Proof-of-Concept strategy and the early Clinical Development Plan. Develop and implement strategies for efficient, high value management of drug development projects leading to clinical Proof-of-Concept and competitiveness of compounds
- Develop and implement disease area and biomarker strategies: contribute effectively to the preclinical and clinical Disease Area strategies, project-specific Biomarker strategy, innovative target identification and in-licensing efforts resulting in a high quality preclinical and clinical portfolio
- Ensure full implementation of studies during the Proof-of-Concept phase by providing medical and scientific leadership and expertise to all line functions on the project team, and direct or supervisory medical support for all pharmacokinetic studies
- Translational Medicine representative to Health Authorities in matters and meetings that focus on early exploratory development: negotiate effectively with Health Authority representatives on all aspects of Translational Medicine and obtain results favorable to Novartis. Translational Medicine representative to Translational Medicine/medically related experts and organizations, advancing the interests of Novartis by your knowledge, style and personal skill and enhancing the position of Novartis with these individuals and groups
- Contribute senior expertise to Research in support of target identification, selection, target validation and preclinical development of compounds. Review and evaluates cross-Disease Area activities at and beyond the early compound optimization stage. Provide clinical context and help design optimal preclinical studies
- Evaluate clinical centers and foster communication with crucial collaborating investigators. Interact effectively with external medical and non-medical leaders and be an internal Novartis expert leader in your scientific and clinical subspecialty field.

Matrix people responsibility per project: 5-8 cross-functional members from Translational Medicine plus other line functions per project team
Impact of this role?
- Design and implementation of early Clinical Development Plan and studies according to the Integrated Development Plan / Clinical Development Plan / Clinical Pharmacology Plan enabling efficient and rational decision-making, high probability of fast drug registration, favorable drug label and high competitiveness of compounds
- This role has a key impact on the entire Novartis pipeline, transitioning programs from preclinical through early clinical and ultimately to full development via the Proof of Concept mechanism, and driving the program after Proof of Concept by delivering key Profiling data to support regulatory submissions
- As a recognized expert in your field, you drive project team clinical strategies and bring global credibility across various Novartis Institutes and Divisions as well as country organizations

**Commitment to Diversity & Inclusion**:

- We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._

**Role Requirements**

This position is written for Director - we can hire Associate Director for those with careers that include less established science / clinical study experience. We support International family relocation and integration support to Switzerland.
What you’ll bring to the role:

- MD and Board certified Rheumatologist (or similar relevant sub-specialty clinical training with directly relevant patient experience) with PhD-level basic science. A completed relevant postdoctoral fellowship is strongly preferred
- Advanced / business-level / fluent English (oral and written)
- Recognized for your medical expertise: an experienced Clinician treating relevant patient groups at an academic medical center or private medical practice group
- Recognized for your scientific expertise: respected by colleagues internally and externally, you’ve made significant contributions to your field and created / established new concepts; you have a record of high quality publications in international scientific journals
- Experience designing and conducting early phase clinical trials including for inflammatory arthritis: either from pharma/biotech, a senior CRO role where you were responsible for the medical relationship and studies with Sponsors, or from a relevant academic

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