Intern Research Associate in Cell Biology

vor 2 Wochen


Basel, Schweiz Monte Rosa Therapeutics, Inc Vollzeit

Overview:
If you have an interest in any of the following areas, we will give you hands on educational experience within a high paced Drug discovery environment.

**Responsibilities**:
**Cell Biology**:

- You will investigate degradation of proteins and investigate E3 ligases by various techniques across cancer cell lines.
- You will also have the opportunity to develop and validate orthogonal methods for protein level measurements.
- You will be attending and presenting your data at the team and project meetings.

**Qualifications**:

- Our preference is for a student currently in a Master degree program in Cell Biology, molecular biology, or a life science.
- Strong desire to learn the most advance approaches to drug discovery
- Cell Biology centric individuals should have previous experience with mammalian cell culture, and typical cell biology techniques (e.g. Viability assays, ELISA, Western Blot, PCR).
- Enjoys working in a team-based environment.

**Molecular biology**:

- You will develop and validate an automated molecular cloning platform for multi-fragment DNA assembly, using various lab automation technologies.
- You will employ this workflow to investigate molecular glue-induced E3 ligase-neosubstrate protein-protein interactions, thereby supporting the company’s drug discovery pipeline.
- You will be presenting your findings at team and project meetings.

**Qualifications**:

- Our preference is for a student currently in a master’s degree program in cell Biology, molecular biology, biochemistry or a related field.
- Strong desire to learn advanced approaches in lab automation and molecular cloning.
- Previous experience in molecular cloning (classical restriction-ligation or Golden Gate, Gateway, Gibson Assembly), including know-how in culturing bacteria, PCR, DNA electrophoresis and DNA/RNA purification.
- Experience with mammalian cell culture is an advantage, but not required.
- Is a fast learner and enjoys working in a team-based environment.



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