Internship - Screening of Computationally Designed

vor 2 Monaten

Schlieren, Schweiz Molecular Partners AG Vollzeit

**General information**:
**Reference **:2024-168

**Information about Molecular Partners AG**:
Molecular Partners AG is a clinical-stage biotech company pioneering the design and development of DARPin therapeutics for medical challenges other drug modalities cannot readily address. Founded in 2004 by a group of PhD students from the University of Zurich, we are a team of about 180 dedicated and passionate colleagues with operations in Switzerland and the U.S. DARPin (Designed Ankyrin Repeat Protein) therapeutics are a new class of custom-built protein drugs based on natural binding proteins that open new dimensions of multi-functionality and multi-target specificity in drug design.

DARPin therapeutics have been clinically validated across several therapeutic areas, including oncology, ophthalmology and virology, and we have programs in various stages of pre-clinical and clinical development, spanning immuno-oncology and targeted Radio-DARPin therapy.

Through our 20 years of leadership and experience with DARPins, as well as through partnerships with leading pharmaceutical companies such as Novartis and Orano Med, we are committed to bringing novel, life-changing therapies to patients.

We seek passionate, creative, and dynamic individuals to join us on our mission.

**Position description**:
**Position title**:
Internship - Screening of computationally designed binding molecules

**Job description**:
Within these challenging projects you will be able to do the following tasks:

- Plan the experimental set-up of your sub-project in an industrial setting.
- Perform experiments with state of the art technologies in molecular biology and biochemistry, including cloning and production of DARPin proteins in E.coli, purification and screening binding hits by ELISA/HTRF and characterization for biophysical properties.
- Ensure that scientific quality is maintained within the project.
- Documentation and presentation of your findings.
- Close interaction and discussion with highly experienced researcher.

**Requirements**:
For this challenging position, we are looking for a highly motivated student in biology or a related discipline with the following skill set:

- Bachelor or Master student in Molecular Biology, Life Science or related field.
- Profound laboratory experience in molecular biology and biochemistry.
- Practical experience with Molecular Biology techniques, such as Cloning, PCR, SDS-PAGE, ELISA, etc.
- High level of independence in planning of experiments and daily tasks.
- Interest in taking responsibility for the progress of your sub-project.
- Ability to read and understand scientific documents/papers.
- Communicative team-player who is open for a constructive feedback culture.
- Familiarity with Windows Office package.
- Due to the international nature of the company, fluency in written and spoken English is necessary.

**Our offer**:

**Position location**:
**Job location**:
Switzerland, Zürich, Schlieren

**Preferred head hunter clause**:
Molecular Partners AG, Wagistrasse 14, CH-8952 Zurich-Schlieren, Switzerland.

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