Research Assistant in the Single-cell Genomics Platform

Vor 2 Tagen


Basel, Schweiz ETH get hired Vollzeit
Research Assistant in the Single-cell Genomics Platform

IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded. We are seeking qualified and highly motivated Research Assistant to support the Single-cell Genomics Platform.

Your responsibilities
  • Isolate and prepare single cells from various eye tissues and cultures; perform advanced NGS library preparations, including RNA-seq, Epi Multiome, and CITE-seq using 10x Genomics platforms.
  • Prepare sequencing libraries and operate sequencing instruments such as Illumina and ONT (Oxford Nanopore Technologies).
  • Develop and implement innovative plate-based (e.g., FLASH-seq) and emulsion-based protocols for specialised NGS applications in collaboration with IOB researchers.
  • Contribute to the establishment, optimisation, and implementation of Spatial Transcriptomics methodologies.
  • Maintain and ensure the quality and consistency of existing NGS protocols.
  • Provide technical assistance and expert guidance to IOB researchers for their projects.
Requirements
  • Master’s degree (or equivalent) in Molecular Biology, Biotechnology, or a related field, with substantial hands-on experience in NGS workflows.
  • Proven work experience in cell biology is advantageous.
  • Demonstrated expertise in executing NGS protocols is essential.
  • Familiarity with liquid handling robotic platforms (e.g., Tecan) and automated dispensers (e.g., I.DOT) is desirable; training will be provided if required.
  • Proven ability to independently plan, execute, and troubleshoot NGS experiments.
  • Strong multitasking skills with the ability to manage and prioritise multiple parallel tasks effectively.
  • Willingness to acquire and apply new technical skills on cutting-edge instruments as needed.
  • Passion for developing, refining, and optimising new protocols and experimental techniques.
  • Highly organised, with exceptional attention to detail.
  • Fluency in oral and written English is required.
We offer
  • Competitive salary among the academic world.
  • Five weeks of vacation for all employees, with increasing amount of vacation days by age.
  • Paid maternity leave up to 16 weeks plus the opportunity to extend it through unpaid leave.
  • Opportunities for professional growth and development, including training and education support.
  • Family friendly: we offer childcare subsidy, a family room.
  • The chance to be part of a groundbreaking research institute making a real impact in the field of medical science.
  • Additional discounts and benefits: e.g. cafeteria, access to the Uni Sport offerings at university Basel, and more.
Application / Contact

To apply, please submit your application through our recruiting platform. For more information, visit www.iob.ch. If you have questions after applying, you can contact us by simply replying to the confirmation email you will receive or via jobs@iob.ch.

Please note that we only accept applications via the recruiting portal.

IOB Institute of Molecular and Clinical Ophthalmology #J-18808-Ljbffr

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