Genetics & Genomics Lab research associate (m/f/d)
Vor 2 Tagen
Responsibilities:
- Develop, validate, and implement genetics and genomics-based biomarker assays (e.g., epigenetics, SNVs, CNVs, gene expression signatures, circulating DNA/RNA) to support pre-clinical studies and early-phase clinical trials, characterizing pharmacodynamics and mechanisms of action for novel therapeutics.
- Evaluate and apply cutting-edge genetics and genomics technologies (e.g., single-cell sequencing, spatial-omics, ddPCR) to maximize insights from limited and valuable pre-clinical and clinical samples following Roche GCP standards.
- Deliver high-quality biomarker data to project biology and biomarker teams, ensuring impactful contributions to therapeutic development.
- Ensure compliance with Safety, Health, and Environment (SHE) regulations in all laboratory and operational activities, contributing to a safe and sustainable research environment.
- Inspire and train other scientists and associates in applying novel technologies and facilitate the transfer of innovative methods to external collaboration partners.
Minimum Qualifications:
- Master's degree or higher in molecular biology, biochemistry, or a related field with substantial experience in biomarker assay development in pre-clinical or clinical settings.
- Deep hands-on expertise in molecular biology techniques (e.g., qPCR, ddPCR) and next-generation sequencing (NGS) platforms, including single-cell and spatial-omics technologies.
- Proficiency in developing, validating, and applying genomic assays across multiple platforms and sample types (e.g., tissue, liquid biopsies).
- Familiarity with implementing genetics and genomics assays in compliance with Good Clinical Practices (GCP) is a plus.
- Fluency in English is required; German would be nice to have.
- Ability to think creatively and rigorously in evaluating and developing new technologies for current and emerging scientific modalities.
- Strong focus on ensuring operational compliance in the storage, tracking, and management of samples and data, adhering to established regulatory and organizational standards.
- Strong team player with a collaborative spirit, able to work independently and within agile, matrixed teams.
Nice to Have:
- Previous Pharma experience.
Application Process:Interested? Please apply via the "Bewerben" button below and answer all questions, otherwise we will be unable to process your application. Please upload your CV in English, along with your degree certificate and latest reference letter. #J-18808-Ljbffr
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