ADS Lead

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche. This role is in Analytical Data Science, a core function within Product Development Data Sciences (PDD) that provides strategic leadership and scientific rigor across Development at Roche. PDD Analytical Data Science teams are mobilized across the portfolio to generate data-driven insights, identify opportunities for scale, and implement impactful solutions. PDD Analytical Data Science is recognized as a leading hub for top industry talent, operating as an agile workforce to deliver regulatory commitments across the portfolio. We identify, influence, and adopt industry-leading digital and automation solutions, develop analytical approaches to support exploratory analyses, and align statistical programming practices across both early- and late-stage clinical development. The Opportunity The Analytical Data Science Lead serves as a senior leader within the Analytical Data Science function, responsible for guiding both the technical strategy and operational execution across multiple clinical programs or an entire therapeutic area. This role leads a team of highly skilled programmers and junior leaders, ensuring the delivery of high-quality, regulatory-compliant analytical outputs that support key development milestones and health authority submissions. In addition to overseeing day-to-day delivery, the Analytical Data Science Lead is accountable for a broad range of analytical outputs including but not limited to: exploratory analyses, application development and dynamic visualization to enable ongoing data review and scientific insights generation. The Analytical Data Science Lead also oversees deliverables originating from cross-functional partners, such as Data Management, ensuring seamless integration into the reporting pipeline. The Analytical Data Science Lead sets priorities, allocates resources, and ensures the scalability and sustainability of programming operations through standardization, automation, and innovation, while providing business context to guide decision-making with evolving portfolio needs. The Analytical Data Science Lead plays a pivotal role in cross-functional planning and governance, acting as a strategic partner to stakeholders across PDD. As a people leader, the Analytical Data Science Lead is accountable for building and developing talent, fostering a culture of technical excellence, and ensuring alignment with both functional and enterprise-wide data strategies. You oversee programming and analytical strategy across multiple molecules or an entire disease area, ensuring alignment with clinical, regulatory, and enterprise data goals You lead cross-functional planning and execution of data deliverables, ensuring quality, consistency, and timeliness across programs, accountable to the TA leads You represent the data science function in high-level internal forums and global regulatory engagements, contributing to the definition and execution of regulatory strategy You resolve complex technical and operational challenges that impact the function’s delivery, quality, or external perception You drive the adoption of innovative programming tools, scalable delivery models, and automation approaches to improve functional performance and sustainability You manage vendor oversight and coordination of external partners to ensure high-quality, efficient, and aligned delivery You shape the broader Product Development Data Science (PDD) agenda by contributing to cross-functional governance, strategic planning, and enterprise-level initiatives You manage a team of ADS Programmers, including workload allocation, performance management, and ongoing development planning You set team strategy and priorities, and execute short-term planning through effective delegation according to allotted resourcing and budgeting You build and sustain a high-performing team by identifying skill gaps, hiring talent, and fostering a culture of excellence, innovation, and collaboration You guide the team through ambiguity, providing direction and support as they navigate complex projects and shifting priorities You serve as the primary point of accountability for team performance and delivery, ensuring that portfolio deliverables – submissions, outputs, applications, and more – meet expectations for quality, compliance, and timelines Who you are: You hold an advanced degree (Master’s or PhD) in Statistics, Biostatistics, Computer Science, Life Sciences, or a related quantitative field You have 12+ years of experience in statistical and analytical programming within clinical development, with demonstrated impact across multiple programs or therapeutic areas You bring deep expertise in clinical trial data standards (e.g., CDISC SDTM and ADaM), regulatory submission requirements, and end-to-end data workflows You have a proven track record of leading cross-functional data delivery for complex clinical programs, including regulatory submissions You are proficient in programming languages and tools commonly used in clinical data analysis (e.g., SAS, R, Python), with experience implementing scalable, reusable, and automated solutions You have a strong understanding of global regulatory expectations and experience representing programming in interactions with health authorities You demonstrate the ability to lead large-scale initiatives and resolve complex technical challenges with minimal guidance You have experience contributing to functional innovation, including the adoption of new tools, standards, or delivery models You demonstrate respect for cultural differences when interacting with colleagues in the global workplace Preferred Qualifications: Experience leading programming strategy for global regulatory submissions, including integrated summaries (ISS/ISE) Familiarity with metadata-driven programming approaches or enterprise-level data standardization Proven ability to drive functional innovation through automation, process improvement, or adoption of emerging tools Exposure to real-world data or digital health integration within clinical development Participation in industry working groups, consortia, or recognized contributions to advancing programming standards or practices Relocation benefits are not available for this posting Let’s build a healthier future, together. Roche is an Equal Opportunity Employer. #J-18808-Ljbffr