Principal Scientist
vor 2 Wochen
SummaryLocation: Basel, Switzerland Full time, onsite, #LI-onsite Disease Area X, a department within the Biomedical Research (BR) group of Novartis, focuses on diseases of critical human organs, including kidney, lung, and liver. We are seeking a scientist to join our interdisciplinary pharmacology team (Discovery and Translational Pharmacology) in support of our efforts to progress novel medicines toward the clinic, with an emphasis on renal diseases. In this role, you will work together with direct reports and drug discovery teams to help lead in the conception, execution, and interpretation of in vivo and ex vivo studies that support target validation and drug candidate progression.
About the Role
Your responsibilities include, but are not limited to:
- Significant contributor or leader of drug discovery project teams who is able to conceive and design in vivo experiments with rodents in support of a portfolio of drug discovery programs. Critical design elements include dosing novel therapeutics; pharmacokinetic and pharmacodynamic analyses; in-life activities including blood and urine collection, ultrasound, metabolic, and similar non-lethal readouts; and harvesting of tissues for analysis of efficacy using molecular biology, cell biology, and histology assessments.
- Lead from the bench in the execution, interpretation, and extracting of next step recommendations for in vivo and ex vivo experiments, primarily of kidney disease, but will likely include work in other therapeutic areas.
- Crisp and compelling communication of project/team strategy, scientific vision, and data to key stakeholders.
- Enabling partnerships with individuals across Biomedical Research Disease Areas and platform functions.
- Leading and/or influencing multi-disciplinary project team(s) to decision milestones.
- Managing, training, and developing a team of research scientists in the pharmacology discipline.
Essential Requirements:
- Ph.D or MD/Ph.D or equivalent training.
- At least 3 years of postdoctoral experience in industry or equivalent.
- Pharmacology expertise in renal biology (preferred) and/or general drug discovery.
- Hands-on experience in executing complex pre-clinical animal model studies, including designing and executing fit-for-purpose drug discovery flow charts and enabling deep mechanistic and pharmacological characterization of lead candidates.
- Team oriented and collaborative work ethic.
- Demonstrated ability to coach and empower others including development of early career scientists.
- Excellent oral and written communication skills in English, German desirable.
Desirable Characteristics:
- Experience in complex cellular models and/or ex vivo systems.
- Experience with leadership, strategic oversight, and project management of successful project team(s).
Why Novartis:
Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us
Learn more here: and culture
We offer plentiful benefits, state-of-the art facilities and helpful resources – all designed to help you thrive personally as well as professionally. You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. rewards
Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: (link is external)
*Restrictions on working flexibility may apply to this position and can be discussed at interview as required
Accessibility and accommodation
Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together?
Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: (link is external)
Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Apply to Job(link is external)Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
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