Principal Scientist I

Vor 7 Tagen


Basel, Basel-Stadt, Schweiz Healthcare Businesswomen's Association Vollzeit

Job Description Summary

Location: Basel, Switzerland
Full time, onsite, #LI-onsite

We are seeking to hire a motivated candidate with a strong background in cellular and molecular immunology to join our Translational Immunology Unit in Basel within our Biomedical Research division.

This is a unique opportunity to apply your deep knowledge of immunology to enable state-of-the-art cross-species immune system safety assessments for novel life-saving medicines during early and late phases of development. In collaboration with preclinical and clinical teams as well as external academic partners, you will lead innovative in vivo and in vitro experimental approaches to assess hazards and risks for drug-induced immunopathology and immune-mediated toxicity. Your contributions will enhance and accelerate the drug discovery and development portfolio of Novartis, bringing forward effective and safe medicines.

Job Description

Your responsibilities include, but are not limited to:

  • Contribute and perform relevant experimental methods and scientific judgement to cross-species immune safety assessments introducing, developing, implementing, validating, and maintaining state-of-the-art technologies and laboratory procedures.
  • Perform target reviews and translational immune system safety assessments for early and late development projects.
  • Interface with internal clinical and preclinical teams and manage external academic collaborations.
  • Interface with regulatory agencies.
  • Present scientific/technical work and achievements at internal / external meetings.
  • Publish results in internal repositories, in peer reviewed journals and as patent applications, as appropriate.

Minimum requirements:

  • Education: MD/DVM and/or PhD with strong experience (3-5 years) in immunology and infection diseases biology.
  • Extensive experimental immunology with a strong research profile in both human and preclinical species.
  • Good understanding of drug-induced immune reactions.
  • Excellent communication skills and fluency in oral and written English.
  • Knowledge of the scientific disciplines involved in drug safety assessment, including relevant laboratory procedures related to safety risk management, as well as experience with large data analysis will be advantageous.
  • Proficiency with major state-of-the-art immunology technologies and approaches.
  • Proven expertise in scientific and technical problem-solving, ideally within an international, multi-disciplinary environment.
  • Proven experience supervising scientists, leading projects and working cross-teams.

Desirable requirements:

  • Excellent scientific publication record.
  • Good scientific network with academic institutions.
  • Proven program and project management skills and conflict solving abilities in matrix environments.

*Restrictions on working flexibility may apply to this position and can be discussed at interview as required

Accessibility and accommodation
Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Skills Desired

Animal Models, Animal Models, Apache Continuum, Bioinformatics, Chemistry, Clinical Research, Collaboration, Communication Skills, Data Analysis, Drug Development, Drug Discovery, Due Diligence, Ethics, Flexibility, Influencing Skills, Job Description, Laboratory, Lifesciences, Line Of Business, Medical Research, Patient Care, Pharmaceutics, Problem Solving, Project Management, Regulatory Compliance {+ 4 more}
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