Principal Scientist
Vor 7 Tagen
Job ID 390562BR
SummaryLocation: Basel, SwitzerlandFull time, onsite, #LI-OnsiteThe Immunology (IMM) department is accommodated within the Biomedical Research department of Novartis and works in collaboration with colleagues from Novartis Research and Development on several therapeutic areas with high unmet need, including autoimmune and inflammatory kidney diseases. Using a diverse array of approaches and ground breaking technology, IMM strives to develop drugs that improve the lives of individuals suffering from autoimmune and inflammatory kidney diseases for which there is currently no cure. At Novartis we have a bold ambition to transform the lives of millions of people living with such diseases.
About the Role We are seeking an innovative, independent and dynamic Principal Scientist with broad expertise in nephrology and immunology to join a discovery biology team focused on developing innovative therapeutic agents in the area of glomerulonephritis.
Your responsibilities will include:
• Contribute to the Biomedical Research drug discovery process with the goal to discover and develop novel therapeutic treatment options for patients with glomerulonephritis.
• Lead drug discovery projects in the renal disease space, propose and champion new targets and novel approaches for disease treatment.
• Contribute to translational research activities and mechanism of action studies to support ongoing clinical development programs
• Design and execute in vitro and in vivo research plans to evaluate targets modulating glomerulonephritis indications.
• Engage in interdisciplinary research requiring the application of specialized scientific knowledge and advanced laboratory techniques, in particular in vitro and in vivo models of glomerular diseases.
• Collaborate with other scientists in a global matrixed dynamic environment fostering innovation and advance project activities. Develop and maintain external relationships/contacts.
What you will bring to the role:
• A PhD and/or MD degree with Postdoctoral experience and a minimum of three years of research in renal biology and/or immunology, preferably in the pharmaceutical / biotechnology industry or academia.
• In-depth knowledge of pathophysiology of autoimmune and inflammatory glomerular diseases, especially around the role of pathogenic autoantibodies in disease i.e. expert in B cell biology, immune complex mediated renal diseases, autoantibody mediated effector function and inflammatory pathways in renal diseases.
• A track record of leading drug discovery projects and working alongside disease areas specialists to bring mechanistic target biology and target validation understanding for renal diseases.
• A proven scientific impact on innovation through a solid publication track record and strong external scientific network with academic experts.
• Excellent oral and written English communication skills, with an ability to effectively interact with people in a dynamic matrix environment, both internally and externally
• Experience in leading and mentoring associates and cross-functional teams
*Restrictions on working flexibility may apply to this position and can be discussed at interview as required
Accessibility and accommodation
Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together?
Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up:
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