Selection and Screening Head

vor 1 Woche


Schlieren, Zürich, Schweiz Molecular Partners AG Vollzeit

General information:

Reference :

Information about Molecular Partners AG:


Founded in 2004 by a group of PhD students as a spin-off from the University of Zurich, Molecular Partners AG is a thriving and steadily growing clinical stage biotech company located in Zurich-Schlieren (Switzerland) with 200 highly qualified employees.


In order to advance modern medicine and significantly improve the management of serious diseases, we have developed and successfully established a powerful new class of potent, specific and versatile small protein therapies, called DARPin therapeutics.

The highly dedicated, multi-disciplined team at MP is committed to developing breakthrough medicines for serious diseases.

Position description:

Position title:

Selection and Screening Head - Lead Generation (100%)

Job description:

This challenging and diverse position will include the following tasks and responsibilities:

  • Supervision of the team performing ribosome display and phage display selections, as well as of the DARPin screening and formatting experts.
  • Maintaining the DARPin leadership by integration of learnings for DARPin improvements into the design of the next generation DARPin libraries with superior properties.
  • Supporting and guiding project teams with selection strategies, tailored to the needs of the targets and indications.
  • Bring the screening technologies to the next level, by implementation of new technologies (automation, digital tools, etc.).
  • Lead DARPin platform initiatives within/adjacent to our pipeline projects to evolve the DARPin scaffold to "teach DARPins new tricks."

Requirements:

For this position, we are looking for an enthusiastic and highly skilled individual who features the following credentials:

  • An agile and dedicated "driver" and team-player who is eager to help bring our DARPin generation platform to the next level.
  • Scientist with a PhD in Biochemistry, structural biology, or related field with 10+ years in a biotech/pharma environment.
  • Proven leadership skills, with successful supervision of a diverse group of lab technicians and scientists.
  • Deep experience in the selection, screening, and characterization of antibodybased, peptidebased and/or alternative scaffold binders.
  • Strong in identifying improvements in our lead generation process pipeline and able to quickly propose and execute remedies.
  • Experience in the integration of digital tools (AI/machine learning) as well as in lab automation in the selection and screening process is considered a plus.
This position summary is not intended to be all inclusive. An employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

Our offer:

Position location:

Job location:

Switzerland, Zürich, Schlieren

Preferred head hunter clause:

Molecular Partners AG, Wagistrasse 14, CH-8952 Zurich-Schlieren, Switzerland.

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