Contractor for Adme
vor 2 Wochen
The Life Science Career Network
Our client is a pioneer in Drug Discovery and Development and is among the frontrunners in Personalised Healthcare.
As the world's largest R&D spender in the pharmaceutical and diagnostics domain, they work across a vast array of drug discovery and therapeutic areas, enjoying high international recognition.
For their headquarters in Basel, Switzerland, we are currently seeking a:Contractor for ADME - Enzymology and DDI
Responsibilities:
- Conduct laboratorybased assays in in vitro enzymology/DDI and allied experimental areas of small molecule drug metabolism, such as incubating test substances using hepatocytes, human liver microsomes, and recombinant enzymes.
- Analyze incubation samples via LC-MS/MS and radioHPLC, including bioanalytical method development and/or validation.
- Plan, monitor, communicate, and report enzymology/DDI studies in both drug discovery and drug development settings, reporting to laboratory staff and supervisors.
- Perform rigorous verification and develop best practices to improve regular enzymology/DDI assays where current approaches are inadequate.
- Some time may be spent supporting the development of new enzyme phenotyping methodologies and approaches with the help of automation.
Requirements:
- BSc or MSc degree in chemistry, biochemistry, pharmacokinetics, or equivalent discipline with an interest in drug metabolism, pharmacokinetics (DMPK), and pharmacodynamics (PD). (Recent PhDs might be considered—please note that this is a laboratoryfocused position.)
- Good knowledge of metabolic enzyme biochemistry (e.g., CYP450, UGT), handson/experimental enzyme kinetics assessment, and respective experimental designs.
- Experience in bioanalytical method development/validation for radioHPLC (e.g., Thermo) and LC-MS/MS (e.g., Sciex). This includes troubleshooting and data analysis (e.g., using Analyst software).
-
In Vitro Adme Scientist
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Novartis VollzeitAs an ADME Scientist with NIBR's Pharmacokinetic Sciences (PKS) organization, you will facilitate the ADME optimization of small molecules across discovery phases. The characterization of the absorption, distribution, metabolism, and excretion (ADME) properties using in vitro assays such as metabolic stability and cellular permeability provides critical...
-
Adme Professional Research Associate in Enzymology
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Coopers Group AG VollzeitADME Professional Research Associate in EnzymologyFor our pharmaceutical client in Basel we are looking for ADME Professional Research Associate in Enzymology.Start date: as soon as possibleDuration: 1 year/possible extensionResponsibilities: Conduct the laboratorybased assays in in vitro enzymology/DDI and allied experimental areas of small molecule drug...
-
Compound Manager. Temporary Contractor
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Monte Rosa Therapeutics AG VollzeitCompound manager. Temporary contractor (3-4 months)Location : Basel, SwitzerlandResponsibilities: Assists the compound managers in organizing the compounds inventory Manually produces solutions from milligram amounts of neat compounds Measures volume of the prepared solutions Tracks various transfer steps through the use of a software system Maintains lab...
-
HR Generalist
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Black Diamond Networks VollzeitHR Generalist / Payroll SpecialistLocation:Basel, SwitzerlandPay:Competitive base salaryWho we're looking for:A focused, competitive, hardworking, and sharp individual who thrives on creating opportunities. At Black Diamond Networks we want energetic, on-the-ground team players like you who are at the top of their game. Please note this position is based...
-
Project Planner/scheduler
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Turner & Townsend VollzeitCompany DescriptionAt Turner & Townsend we're passionate about making the difference. That means delivering better outcomes for our clients, helping our people to realize their potential, and doing our part to create a prosperous society. Every day we help our major Pharmaceutical clients deliver ambitious and highly technical projects worldwide.Are you...
-
Data Science Intern
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Novartis Vollzeit6000 That's the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. As a Data Science Intern, you will join our Modeling & Simulation Data Science team in the...
-
Paralegal
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Swisslinx VollzeitOn behalf of our client, an international pharmaceutical company based in Basel, Swisslinx is looking for a Paralegal. This is a contract for 13 months (maternity leave cover) with a great opportunity to bring your proven knowledge and expertise to an organization that offers a dynamic working environment. Start date: Middle of September Duration: 13 months...
-
Director, Project Initiation Lead
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Lonza VollzeitToday, Lonza is a global leader in life sciences operating across three continents. While we work in science, there's no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small,...
-
Lab Manager, Pharmaceutical Sciences
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Roche VollzeitThe Position In Roche'sPharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world's toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicine. Together, we create a culture defined by curiosity, responsibility and...
-
Engineering and Facilities Manager
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Lonza VollzeitToday, Lonza is a global leader in life sciences operating across three continents. While we work in science, there's no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small,...
-
Junior Electrical Planner
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Hitachi Zosen Inova VollzeitJunior Electrical Planner:Hitachi Zosen Inova AGZürich (Schweiz)Presence / MobileWork experienceEngineerTechnical occupations (other)About us: Zurichbased greentech company Hitachi Zosen Inova (HZI) is a global leader in solutions for energy transition and circular economy including Energy from Waste (EfW) and Renewable Gas (RG), operating as part of the...
-
Compound Manager
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Monte Rosa Therapeutics VollzeitCompound Manager - Temporary Contractor (3-4 Months)Location : Basel, SwitzerlandResponsibilities: Assists the Compound Managers in organizing the compounds inventory Manually produces solutions from milligram amounts of neat compounds Measures volume of the prepared solutions Tracks various transfer steps through the use of a software system Maintains lab...
-
Test Conductor/range Safety Advisor
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Amentum VollzeitAmentum is seeking a Test Conductor/Range Safety Advisor to support the Atlantic Undersea Test and Evaluation Center (AUTEC) Mission in Andros Island, Bahamas. AUTEC is a Major Range and Test Facility Base (MRTFB) and the Naval Undersea Warfare Center, Division Newport's largest single team project, providing both deep and shallow water test and training...
-
Data Management Specialist
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Michael Page VollzeitThe PDP (Personal Data Protection) is not fully implemented, so the contractor will guide business areas and work on a risk-based approach. The role involves 2/3 personal data work and 1/3 general data governance.Partnering with stakeholders to create comprehensive data inventories, mapping the flow of personal data across systems, processes, and third...
-
Construction Manager
vor 2 Wochen
Basel, Basel-Stadt, Schweiz PM Group VollzeitConstruction Manager: Contract Onsite Basel, Switzerland Engineering 7326**Overview We have an requirement for experienced Construction Project Manager to join the PM Group. For this role, we need someone who has the capability to manage Mechanical Construction activities for large scale pharmaceutical construction project. This is a Site Based Role in...
-
Legal Assistant
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Proclinical AG VollzeitLegal Assistant Proclinical AG is seeking a detail-oriented and proactive Legal Assistant to join the dynamic legal team. In this role, you will play a crucial part in ensuring the smooth functioning of clients' non-Swiss EMEA and APAC subsidiaries, as well as contributing to the efficiency of Swiss entities. This is an exciting opportunity for a highly...
-
Vice President, Medicinal Chemistry
vor 2 Wochen
Basel, Basel-Stadt, Schweiz LifeMine VollzeitOur CompanySummaryWe are seeking an accomplished, and passionate drug hunter to lead our expanding Medicinal Chemistry Team across multiple sites. The successful applicant will have a proven track record of creativity, innovation, and leadership across all facets of drug discovery, with a broad and deep knowledge of Medicinal and Synthetic Chemistry. This...
-
Logistikmitarbeiter (w/m/d)
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Avantor VollzeitThe Opportunity: Avantor sucht einen motivierten Logistikmitarbeiter (w/m/d) für die umfangreiche Ausübung laborlogistischer Tätigkeiten. Es handelt sich hierbei um eine unbefristete Vollzeitposition. Ihr Einsatzort wäre unser Kundenstandort, ein führendes Pharmaunternehmen in Basel. Neben einer attraktiven Grundvergütung und geregelten...
-
Facilities Site Leader
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Amentum VollzeitAmentum is seeking a Facilities Site Leader to support the Atlantic Undersea Test and Evaluation Center (AUTEC) Mission in Andros Island, Bahamas. AUTEC is a Major Range and Test Facility Base (MRTFB) and the Naval Undersea Warfare Center, Division Newport's largest single team project, providing both deep and shallow water test and training environments....
-
Site Leader
vor 2 Wochen
Basel, Basel-Stadt, Schweiz Amentum VollzeitAmentum is seeking a Site Leader - AUTEC Site 2 to support the Atlantic Undersea Test and Evaluation Center (AUTEC) Mission in Andros Island, Bahamas. AUTEC is a Major Range and Test Facility Base (MRTFB) and the Naval Undersea Warfare Center, Division Newport's largest single team project, providing both deep and shallow water test and training...