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(Senior) Research Associate CMC Process Development
vor 3 Monaten
Our client is a start-up biotech company specialized in the development of glycoengineered biologics and is located near Zürich, Switzerland. Our client's CMC Process Development and Analytics team is responsible for developing, optimizing, and scaling up upstream and downstream manufacturing processes for tox and clinical drug supply, and developing analytical assays for final product release testing, product characterization, and supporting product- and process development.
Tasks- Developing robust purification processes, unit operation steps and in-process control methods for the purification of our drug candidates.
- Performing batch purifications and characterization of recombinant glycoproteins.
- Planning and executing process and know-how transfer to external parties and supervising ongoing work.
- Performing experiments according to established plans, timelines, and priorities.
- Maintaining infrastructure & equipment in the area of responsibility.
- Proactively providing solutions to technical and scientific problems.
- Processing, evaluating, and reporting of data as well as presentation in scientific meetings.
You have a proven track record in CMC process development, biochemistry, including protein purification, characterization, and protein engineering. You are experienced in developing GMP-compliant purification procedures for glycoproteins and antibody formats. You have an advanced education and substantial practical experience in biochemistry, bioprocessing, or similar field.
- MSc in biochemistry, molecular biology, bioengineering, or another relevant field.
- 4+ years of hands-on experience in industrial CMC process development with GMP exposure for the purification of therapeutic proteins.
- Practical hands-on experience in TFF, UFDF unit operation step development.
- Extensive practical experience in chromatography process development with a variety of separation techniques.
- Good IT-skills (Excel, databases, statistical software).
- Very good communication skills in English, written and verbal.
- Excellent planning and strong organizational skills, able to manage multiple tasks simultaneously and set priorities.
- Pro-active and problem-solving attitude.
- Personal resilience, perseverance, energy and drive.
- Self-motivation and ability to work independently in a fast-pace, small company environment.
- Excellent interpersonal and negotiation skills.
- Team player, collaborative attitude.
- Innovative science
- Start-up culture
- 5 Weeks vacation
- Career Opportunities
If you are a flexible, self-reliant, and dutiful person willing to bring projects to success, we are eager to hearing from you