Scientist Process Development

vor 1 Monat

Zurich, Schweiz Doris Fink Recruiting & Consulting GmbH Vollzeit

Our client is a start-up biotech company and located near Zurich, Switzerland. The company develops novel biologics for a wide range of indications.

Tasks
  • Plan, design, and conduct experiments for process development studies with minimal supervision.
  • Proactively research literature to identify potential substantial improvements and translate them into scientifically sound experimental plans.
  • Use bioprocessing experience to identify critical process parameters that affect upstream performance.
  • Explore and apply appropriate analytical tools to extend the metabolic understanding of the organism and fermentation processes.
  • Perform routine bioreactor runs for protein production activities.
  • Record data and results in lab notebooks, perform data analysis and present data in lab and development team meetings.
  • The laboratory activities include preparatory activities, shake flask and bioreactor cell culture operations:
  • media and buffer preparations according to standard operating procedures (SOPs), ensuring accurate measurements, proper mixing, and sterilization.
  • prepare and set up bioreactors for cell culture, including sterilization, assembly, and installation/calibration of sensors and probes.
  • Setup shake flasks in shaker incubators for Preculture and perform shake flask trials.
  • Monitor and maintain bioreactor conditions throughout the culture process, including offline measurements such as Optical Density, Cell counts, Cell viability, Glucose, osmolality, pH, conductivity, and other measurements on a routine basis.
  • Perform additional cell culture operations, such as preculture, inoculation and harvesting. Harvesting includes centrifugation and sterile filtration.
  • Follow all established SOPs and guidelines to ensure the integrity of cell cultures, prevent contamination, and maintain compliance.
  • Manage inventory of cell culture reagents, media components, and other consumables to prevent shortages and ensure uninterrupted operations.
  • Participate in training and development opportunities to stay current with industry best practices and emerging technologies.
  • Provide subject matter expertise for processes and equipment and perform tech transfer to external labs and CDMOs. Support scale-up and large-scale bioreactor runs at external manufacturing sites.
  • Supervise a junior RA to support routine productions.
Requirements

You have a proven, hands-on track record in biochemistry and protein analytics and/or have considerable relevant professional experience. If you are a self-sufficient, flexible, reliable, and precise person, meet the requirements listed below and are willing to bring projects to success, we are looking forward to hearing from you

  • PhD or Master’s degree in Cell Biology, Biochemistry, Biotechnology, or a related field preferred.
  • Minimum of 5 years of relevant experience in a fermentation/ cell culture laboratory setting.
  • At least 3 years of industrial experience in biotech/pharma.
  • Hands on experience in process development and good understanding of cell culture techniques, aseptic procedures, bioreactor operations.
  • Proven ability to work independently and as part of a team.
  • Previous experience with either microbial and/or mammalian cell culture required.
  • Excellent organizational and time management skills.
  • Meticulous attention to detail and a commitment to quality control.
  • Ability to work in a fast-paced and demanding environment.
  • Excellent verbal and written communication skills in English
  • Good IT-knowledge (Excel, PowerPoint, databases)
  • Pro-active and problem-solving attitude
  • Self-motivation and ability to work independently in a fast-pace, small company environment
  • Excellent interpersonal and negotiation skills
  • Team player, collaborative attitude.
Benefits
  • 5 Weeks vacation
  • Career Opportunities
  • Well connected office
  • Innovative science


  • Downstream Process Scientist

    vor 2 Wochen

    Zurich, Schweiz Modis Vollzeit

    One of our client in Bern is currently looking for a Downstream Process Scientist for a 12 Months contract. **Profile**: The person should be a Scientist by training and should have biotech/biochemistry background with the interest and willingness to work in the lab. - Master degree or higher plus industry experience with downstream processes for...

  • Research Scientist

    vor 3 Wochen

    Zurich, Schweiz Jacobs Center for Productive Youth Development Vollzeit

    Jacobs Center for Productive Youth Development_ **Research Scientist (for 18 months)** **60 % **:The Jacobs Center for Productive Youth Development is a scientific center at the University of Zurich focused on youth development. The Center is a joint venture between the University of Zurich and the Jacobs Foundation. We are dedicated to interdisciplinary,...

  • Formulation Scientist

    vor 1 Woche

    Zurich, Schweiz Institute of Pharmacology and Toxikology, Group of Prof. Gerald Schwank Vollzeit

    Institute of Pharmacology and Toxikology_ **Formulation Scientist** **80-100 % **:The position is in the research group of Prof. Gerald Schwank at the Institute of Pharmacology and Toxicology. The lab is located at campus Irchel of the University of Zurich. **Your responsibilities**: We are searching for a highly motivated and innovative Lipid Nanoparticle...

  • Research / Data Scientist (Postdoc)

    vor 2 Monaten

    Zurich, Schweiz Jacobs Center for Productive Youth Development Vollzeit

    Jacobs Center for Productive Youth Development_ **Research / Data Scientist (Postdoc)** **100 % **:The Jacobs Center for Productive Youth Development is a scientific center at the University of Zurich focused on youth development. The Center is a joint venture between the University of Zurich and the Jacobs Foundation. We are dedicated to interdisciplinary,...

  • Research / Data Scientist (Postdoc)

    vor 3 Wochen

    Zurich, Schweiz Jacobs Center for Productive Youth Development Vollzeit

    Jacobs Center for Productive Youth Development_ **Research / Data Scientist (Postdoc)** **100 % **:The Jacobs Center for Productive Youth Development is a scientific center at the University of Zurich focused on youth development. The Center is a joint venture between the University of Zurich and the Jacobs Foundation. We are dedicated to interdisciplinary,...

  • Product Development Process Manager

    vor 2 Wochen

    Zurich, Schweiz ABB Vollzeit

    **Product Development Process Manager**: **Take your next career step at ABB with a global team that is energizing the transformation of society and industry to achieve a more productive, sustainable future. At ABB, we have the clear goal of driving diversity and inclusion across all dimensions: gender, LGBTQ+, abilities, ethnicity and generations. Together,...

  • Scientist Cmc Process Delevopment

    Vor 3 Tagen

    Zurich, Schweiz SwisSolution Human Capital AG Vollzeit

    Are you looking for a role in CMC development and you have a strong background in protein biochemistry? Then keep reading! Tasks - Performing batch purifications and characterization of recombinant glycoproteins - Planning and executing process and know-how transfer to external parties and supervising ongoing work - Performing experiments according to...

  • Clinical Scientist, Late Stage Development

    vor 1 Woche

    Zurich, Schweiz Denali Therapeutics Vollzeit

    **Clinical Scientist,** Late Stage Clinical Development** **The Opportunity** Denali Therapeutics is dedicated to developing breakthrough therapies for neurodegenerative and rare diseases through our deep commitment to degeneration biology and principles of translational medicine. In anticipation of the Company's growth plans, Denali Therapeutics is...

  • Manufacturing Scientist

    vor 2 Wochen

    Zurich, Schweiz CTC Resourcing Solutions Vollzeit

    **The Life Science Career Network** For our client, a worldwide leading Pharma and MedTech company with several sites in Switzerland, we are looking **MANUFACTURING SCIENTIST (Combination Products)** located north of Zurich, for a 12 months contract, eventually to be extended. **Requirements**: - Familiarize with company's combination product...

  • Scientist in Cell Line Development at Philochem Ag

    vor 2 Wochen

    Zurich, Schweiz Philochem AG Vollzeit

    Job Title: SCIENTIST IN CELL LINE DEVELOPMENT AT PHILOCHEM AG - Location: Zurich - Switzerland - Department: Others **Who we are**: **Job description**: **Responsibilities**: - Generate high-yield cell lines for the GMP production of therapeutic proteins. - Perform all laboratory work related to cell line development and contribute to the writing of...

  • Vp Process Development

    vor 3 Wochen

    Zurich, Schweiz Batterman Consulting Basel AG Vollzeit

    **Making protein degradation possible****: **Our client** GlycoEra AG is a start-up biotech company specialized in the development of glycoengineered biologics and is located in a biotech hub near Zurich, Switzerland. With her CustomGlycan Platform, they aim to unlock the power of glycan-mediated biology to develop novel biologics for a wide range of...

  • Experienced Data Scientist: Algorithm Development

    vor 2 Wochen

    Zurich, Schweiz greenTEG AG Vollzeit

    greenTEG, a spin-off of ETH Zurich, is developing innovative sensor solutions targeting the wearables market. For the development of algorithms to detect and track physiological parameters, we are looking for a data scientist with expertise in modeling physiological time-series data. Tasks As part of the R&D team, you will - prepare and analyze recorded...

  • Experienced Data Scientist: Algorithm Development

    vor 2 Wochen

    Zurich, Schweiz greenteg AG Vollzeit

    greenTEG, a spin-off of ETH Zurich, is developing innovative sensor solutions targeting the wearables market. analysis or early detection of diseases. For the development of algorithms to detect and track physiological parameters, we are looking for a data scientist with expertise in modeling physiological time-series data. **Preferred start date**:...

  • Vp Process Development

    vor 2 Monaten

    Zurich, Schweiz Batterman Consulting Basel AG Vollzeit

    Our client GlycoEra AG is a start-up biotech company specialized in the development of glycoengineered biologics and is located in a biotech hub near Zurich, Switzerland. With her CustomGlycan Platform, they aim to unlock the power of glycan-mediated biology to develop novel biologics for a wide range of indications. For the future development and in...

  • Vp Process Development

    vor 3 Wochen

    Zurich, Schweiz Batterman Consulting Basel AG Vollzeit

    Our client GlycoEra AG is a start-up biotech company specialized in the development of glycoengineered biologics and is located in a biotech hub near Zurich, Switzerland. With her CustomGlycan Platform, they aim to unlock the power of glycan-mediated biology to develop novel biologics for a wide range of indications. For the future development and in...

  • Senior Research Associate Process Development

    vor 1 Monat

    Zurich, Schweiz Doris Fink Recruiting & Consulting GmbH Vollzeit

    Our client is a start-up biotech company and located near Zurich, Switzerland. The company develops novel biologics for a wide range of indications.TasksPlan, design, and conduct experiments for process development studies with minimal supervision.Proactively research literature to identify potential substantial improvements and translate them into...

  • R&d Scientist

    vor 2 Monaten

    Zurich, Schweiz ITech Consult Vollzeit

    **R&D Scientist** (f/m/d)**- protein production /HTS-Scale cell / synthetic biology / Cell biology /gene cloning / hands-on** **Project**: For our customer Roche Glycart based in Zürich / Schlieren we are looking for a highly qualified Business Operations Manager (M/F/D). Background: We are seeking a highly motivated and skilled cell engineering scientist...

  • Medical Affairs Scientist

    vor 3 Wochen

    Zurich, Schweiz Pfizer Vollzeit

    Medical Affairs Scientist (M/F/d) 80-100% The Medical Affairs Scientist (MAS) is the medical scientific companies’ Point of Contact for HCPs, medical societies, regulators, academia, and other external scientific stakeholders. The MAS is responsible for maintaining the highest scientific standards, independence, and compliance in every...

  • Lead Scientist Lc-ms

    vor 2 Monaten

    Zurich, Schweiz Celerion Vollzeit

    Due to the steady growth of our company and to strengthen our bioanalytical laboratory in Fehraltorf / Zurich, we are looking for a **Lead Scientist LC-MS & MetID (100%)** **Your main **responsibilities** - Manage and lead a team of 4 LC-MS & MetID scientists - Ensure that robust LC-MS bioanalytical assays for small and large molecules are developed...

  • Research Scientist, Computer Vision

    vor 2 Monaten

    Zurich, Schweiz Meta Vollzeit

    At Reality Labs, we’re developing the input technologies that will define the future of the virtual and augmented reality computing platforms. We are looking for a creative, skilled and motivated Research Scientist to join our machine perception team in advancing the state-of-the-art of human understanding, action recognition and statistical text decoding....