Formulation Scientist

vor 1 Woche


Zurich, Schweiz Institute of Pharmacology and Toxikology, Group of Prof. Gerald Schwank Vollzeit

Institute of Pharmacology and Toxikology_
**Formulation Scientist**
**80-100 % **:The position is in the research group of Prof. Gerald Schwank at the Institute of Pharmacology and Toxicology. The lab is located at campus Irchel of the University of Zurich.

**Your responsibilities**: We are searching for a highly motivated and innovative Lipid Nanoparticle Formulation Scientist. In this role, you will be responsible for lipid nanoparticle formulation design, development, characterization and scale up to support emerging research projects in oncology, genome editing and autoimmune disorders.

The role involves manly hands-on laboratory work and some mentoring and training of junior scientists.

You will
- Independently design and develop lipid based nucleic acid formulations with or without targeting modalities.
- Demonstrate creativity and independence in developing, optimizing, and advancing process platforms for various complex nucleic acid formulations.
- Develop or contribute to the development of analytical methods for physico-chemical characterization of lipid nanoparticle conjugates.
- Prepare scientific reports, technical reports, presentations, and experimental protocols as needed.
- Deliver high quality results in an accurate and a time sensitive manner.
- Review scientific literature, patents, scientific abstracts to stay up to date on the latest in the field. Provide scientific expertise in the organization, with special emphasis on lipid nanoparticle-based drug targeting delivery systems for nucleic acids.
- Demonstrate scientific excellence through filing patents and publishing scientific articles in peer-reviewed journals.

**Your profile**: M.S. or Ph.D. in Chemistry, Biochemistry, Bioengineering, or Pharmaceutical Sciences, preferably with 2- 5 years of industry experience in designing and developing nanoparticle-based drug delivery systems or complex biologics.

Experience with lipid nanoparticle formulation and purification processes, or experience with process development, engineering and manufacturing of biologic drug product processes are highly desired.

You must possess an in-depth understanding of all aspects of formulation development as well as downstream characterization including physicochemical, stability and biological evaluation.

Experience in developing liquid, frozen or lyophilized formulations of lipid based nucleic acid formulations is required.

You demonstrated the ability to establish new capabilities and innovate strategies in pursuit of scientific excellence. You must be an independent thinker with a passion for developing innovative formulation technologies.

**What we offer**: We offer stimmulating and inspiring work in a pleasant environment.

**Place of work**: University of Zurich, Campus Irchel, Winterthurerstr. 190, Building Y17, 8057 Zurich

**Start of employment**: To be mutually agreed.



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