Value Chain Product Lead within Cell and Gene Therapy

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Roche Pharma Global Technical Operations (PT) delivers a fast evolving portfolio of new Cell & Gene Therapy (CGT) products to bring new curative treatments to patients. This portfolio of new products comes with the great promise to bring unprecedented medical advances to patients but also presents unique challenges as the Regulatory landscape is evolving very quickly. 

The Value Chain Product Lead (VCPL) in Cell and Gene Therapy holds end-to-end (E2E) Value Chain ownership for specific CGT products. This is a crucial matrix leadership role, accountable for ensuring products achieve E2E Value Chain readiness for upcoming clinical trials and/or commercial launches. The specific responsibilities will adapt based on the product's phase (early/late clinical, commercial launch), partnership structures, and targeted timelines.

Key Attributes & Collaboration

• Thrives in ambiguous, fast-paced environments, demonstrating strong learning agility, excellent communication, and stakeholder management skills.

• Collaborates closely with cross-functional teams (Technical Development, Clinical, Commercial, GPS) and external CDMOs; contributes to new system/process development.

Core Responsibilities

• Leads and manages E2E Value Chain product teams (OEM, Patient Ops, Supply Chain), overseeing schedules, risk logs, and ensuring operational delivery aligned with CMC Roadmaps and TDT/TPT commitments.

• Manages supply chain planning across all product lifecycle phases, driving effective stakeholder management (PTC/Commercial) and partnering with E2E VC Capability Leads.

• Orchestrates day-to-day operational activities for flawless E2E value chain execution supporting patient treatment.

Key Responsibilities & Job Requirements

• Owns comprehensive product plans and forecasts (OEM, Patient Ops, Supply Chain/Logistics) to ensure delivery across CMC, Clinical, and Commercial timelines; leads commercial S&OP.

• Manages daily manufacturing partner interactions for personalized therapy delivery (scheduling, capacity, allocation); acts as key decision-maker for product risks, collaborating with Capability/VC Strategy Leads and CSCL for comparator supply.

• Defines key processes (e.g., ordering, slot management) and provides user requirements for E2E capabilities (e.g., ATHEROS CoC/CoI); leverages ERP experience for system design.

• As a Technical Development Team member, brings Value Chain risks/opportunities to SMEs (Regulatory, Formulations, Process Engineering, Quality); coordinates label design/compliance and new product/country configurations with Master Data Management.

• Coaches colleagues and leads complex products (late-stage, multiple trials) driving proactive strategy and direction.

We're looking for a highly adaptable individual who thrives in a continuously evolving and often ambiguous environment. You'll be a team player excited to take on a range of responsibilities, from tactical roles to strategy projects. You'll also possess excellent verbal and written communication skills, with a proven ability to succinctly share information and influence decisions across all levels. The ideal candidate will demonstrate effective collaboration skills, working seamlessly within highly matrixed cross-functional teams and with external partners. You'll also need the ability to work effectively in a dynamic, fast-paced environment and adeptly manage change, readily embracing new challenges and shifting priorities.

Furthermore, you bring the below qualifications and experience:

• Master's or Bachelor's degree in management, engineering, and/or sciences and/or supply chain is preferred. 

• 12+ years (10+ years with Masters) of work experience in matrix leadership, clinical trial set-up, supply chain planning, and supporting systems (eg. SAP, scheduling, MRP, CGT Orchestration, etc.) in either a clinical or commercial environment. 

• Experience with cell and gene therapy supply chain design and management in the pharmaceutical/biotech industry is a plus. 

• Experience with successfully leading complex cross-functional projects which demonstrated an ability to think creatively and drive for results.

This position requires 10-20% domestic and international travel and is based out of South San Francisco and/or Basel. Plan for hybrid working (part in person and remote every week). Expectation to be in person for key workshops and meetings. Global hours are expected (7am-9am PT/ 4-6pm CET). 
 

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.

Roche is an Equal Opportunity Employer.