Research Associate, Cmc Development

Vor 7 Tagen


Basel, Schweiz Ridgeline Discovery GmbH Vollzeit

**Cimeio Therapeutics is looking for a (Senior) Research Associate, CMC Development - Cell Therapy **.** *

**Cimeio Therapeutics** is an applied gene editing, cellular, and immunotherapy company developing a portfolio of Shielded-Cell & Immunotherapy Pairs for patients with debilitating and life-threatening diseases. Cimeio’s proprietary technology platform is based on the discovery of novel protein variants, which when inserted into cells allow them to preserve function while resisting depletion by a precisely paired immunotherapy. This technology has significant therapeutic potential, which Cimeio is using to develop curative treatments for patients with genetic diseases, hematologic malignancies, and severe autoimmune disorders.

This Basel based position offers a tremendous opportunity to support our growing company in an experienced, vibrant, and agile biotech team.

**RESPONSIBILITIES**
- Participate in the development of a GMP-compliant manufacturing process and control strategy for cell-based products
- Support planning and execute cell culture methods and analytical methods needed to establish consistent manufacturing processes for cellular products
- Support evaluation and implementation of technologies and materials required for successful manufacturing cell therapy products
- Detailed documentation of the experimental lab work (protocols, reports)
- Support organization and maintenance of laboratory supplies
- Review and/or assist in writing of technical documents including laboratory SOPs, protocols and reports
**QUALIFICATIONS**
- BSc or MSc degree in life sciences or Apprenticeship as biological laboratory technician or similar
- 2+ years direct experience with aseptic cultivation of mammalian cell lines and/or primary cells, preferably hematopoietic stem cells (HSC)
- Direct experience with various of the following analytical methods: flow cytometry, qPCR, ddPCR, NGS, ELISA, cell-based assays, CFU assays
- Ability to work independently, organize and prioritize work
- Self-organizer, keen attention to detail
- Ability to acquire knowledge quickly in dynamic start-up environment
- Experience working with MS suite tools
- Good communication skills in English and German, both oral and written
- Experience with working in a regulated environment would be of advantage
**WHAT WE CURRENTLY OFFER**
- **Offices**: Our well-equipped laboratories and offices are located at the Technologiepark, a premier address for early-stage start-ups in Basel.
- **Commuter Benefits**:We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution.
- Flexible Working: We support flexible working as appropriate.
- **Christmas Closure**:In addition to the 24 holidays per year, our offices/labs are closed between Christmas and New Year.
- **Birthday Retreat**: On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off.
- **Food**:We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge.
- **Coffee**: Meet up with your colleagues and grab free coffee.
- **Development**:We support the individual development of our employees.
- **German Lessons**: For our international employees we support German lessons to speed up integration.
- **Creativity**:We offer an innovative and creative environment.
- **People**:We are an international and diverse team with talented and passionate people.
- **Fun**: From time-to-time we organise cool off-site summer and winter team events.



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