Molecular Cell Biology Research Assistant
vor 17 Stunden
The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated **Research Assistant** to join the Human Retinal Circuits Group at IOB, led by Botond Roska.
The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded.
The Human Retinal Circuits Group investigates the visual system across multiple model systems using an interdisciplinary approach combining physiological and molecular methods. Acquired knowledge is directly used to further our understanding of the underlying mechanism causing visual diseases, thereby paving the way for developing transformative medicines. In collaboration with the Retinal Organoid Platform, various in vitro disease models are being created using genome engineering to test novel gene-therapy approaches for human blinding disorders.
We are looking for an individual with interest and determination to contribute to developing the next generation of therapies that improve the lives of patients suffering from devastating vision-impairing diseases. Your main responsibility is to establish organoid-based disease models via gene-editing agents and maintain these under the supervision of senior research colleagues in the Human Retinal Circuits Group. You will also be involved in screening, identifying, and optimizing different treatment modalities such as AAV-based gene therapies.
**Your position**
- In vitro culture of human pluripotent stem cells and retinal organoids
- Genome engineering of pluripotent stem cells by CRISPR/Cas9 and characterization of mutations
- Vector construction and molecular cloning
- Analysis of retinal organoids by various histology and microscopy techniques
- Close collaboration with members of the Human Retinal Circuits Group and Retinal Organoid Platform.
**Your profile**
- Biologielaborant/in (or equivalent education) with several years of work experience or Bachelor's/Master's Degree (or equivalent) in molecular biology or related field
- Excellent aseptic cell culture technique
- Independence in the planning, conductance, analysis, and troubleshooting of standard molecular biology experiments
- Willingness to work with lentivirus, AAVs, and human tissue,
- Enthusiasm to establish and optimize new protocols and techniques
- Highly organized, detail-oriented, and skilled with computers
- Good written and verbal communications skills
- Fluency in oral and written English
**We offer you**
- Highly competitive conditions in a dynamic and international research community in Basel
- IOB is an equal-opportunity employer with family-friendly work policies
**Application / Contact
-
Research Assistant in Molecular Cell Biology
vor 17 Stunden
Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel VollzeitThe Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated **Research Assistant** to join the Human Retinal Circuits Group at IOB, led by Botond Roska. The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is a research institute combining basic and clinical research. Its mission is to drive innovations in...
-
Research Assistant Molecular and Cell Biology
Vor 7 Tagen
Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel VollzeitIOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded. We are seeking a dynamic and driven individual to join our team as...
-
Basel, Schweiz Universität Basel Vollzeit**About us**: IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded. We are seeking a dynamic and driven individual to...
-
Research Assistant in Single-cell Genomics
vor 17 Stunden
Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel VollzeitThe Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated **Research Assistant **to join the Single-Cell Genomics Platform. IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a...
-
Basel, Schweiz IOB - Institute of Molecular and Clinical Ophthalmology Basel VollzeitThe Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking an experienced and highly motivated Research Associate to join the Translation Group led by Dr. Bence György. IOB is a research institute that combines basic and clinical research. Our mission is to drive innovations in understanding vision and its diseases, and develop new...
-
Research Assistant at Single Cell Genomics Platform
vor 2 Wochen
Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel VollzeitIOB - Institute of Molecular and Clinical Ophthalmology Basel - Basel Employees per arrangement **About us**: IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your...
-
Research Assistant
vor 2 Wochen
Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel VollzeitIOB - Institute of Molecular and Clinical Ophthalmology Basel - Basel Employees 1 Year limited per arrangement **Research Assistant/Associate, Molecular Mechanisms of Myopia (100%) - Ref.: IOB158** The global surge in Myopia (or near-sightedness) has reached epidemic proportions and represents one of the most significant public health challenges of our...
-
Basel, Schweiz The Biozentrum, University of Basel VollzeitYour position Hands-on development of a novel stem cell therapy for corneal regenerationEstablish, optimize, and routinely perform stem cell culture, expansion, and characterizationDirectly execute ex vivo genome editing experiments in primary stem cells using base and prime editingPerform functional in vitro assays to assess stem cell identity,...
-
Laboratory Technician
Vor 6 Tagen
Basel, Schweiz Universität Basel Vollzeit**Laboratory Technician - Biochemistry & Molecular Biology** **50% / 01.01.2026** The Nash Lab (University of Basel, Chemistry & ETH Zurich D-BSSE) is seeking a reliable and skilled Laboratory Technician to manage and support day-to-day wet-lab operations in our research program. The role has a potential to grow into a long-term contribution to the...
-
Basel, Schweiz myScience VollzeitResearch Associate, Cell Therapy Translational Research (100%) University of Basel Workplace Basel - North West Switzerland - Switzerland Category Health | Life Sciences Position Senior Scientist / Postdoc Published 20 January 2026 Research Associate, Cell Therapy Translational Research (100%) Ref.: IOB165 The Institute of Molecular and Clinical...
