Postdoc Position in Chemical Biology

Vor 7 Tagen

Zurich, Schweiz Department of Chemistry Vollzeit

_Department of Chemistry_
**Postdoc Position in Chemical Biology**
**75 %**:A Postdoc position is available in the group of Prof. Dr. Nina Hartrampf in the Department of Chemistry at University of Zurich (Switzerland). Our group is interested in the chemical synthesis and modification of peptides and proteins. As part of a collaboration with Novartis Institutes for BioMedical Research (NIBR), we aim to investigate the role of small regulatory proteins and their biological role in cancer progression. To study those, we prepare synthetic analogues and characterize their binding interactions in biochemical and cellular assays.

**Your responsibilities**:
This interdisciplinary project combines a variety of disciplines and tools in the broader field of chemical biology. You will design and synthesize several small proteins of interest using our state-of-the-art fully automated synthesis platform. You will be driving the characterization of these chemically synthesized proteins using various analytical techniques (UHPLC, LCMS, NMR, CD, X-Ray, etc). To elucidate their biological role and function, you will work with biochemical, biophysical, and cellular assays to analyze and quantify the binding interactions between the small protein (and derivatives thereof) and its binding partner(s).

**Your profile**:
**What we offer**:
We offer an exciting position in a stimulating and challenging environment at the interface of chemistry and biology. You will be trained in state-of-the-art SPS technology, protein purification and analysis, chemical biology and organic chemistry. Together with NIBR scientists you will be leveraging the Novartis scientific infrastructure and expertise to advance your project. With this joined research project you will be exposed to both the world-class academic environment of the University of Zurich and the global drug discovery network of NIBR.

**Place of work**:
University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland

**Start of employment**:

- letter of motivation
- curriculum vitae
- short summary of past research accomplishments
- transcripts of your academic records from your University, and a copy of your degree
- contact details of two referees (e.g. your Ph.D. thesis supervisor)

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