Bioinformatics Scientist

Wyss Zurich_
**Bioinformatics Scientist**
**100 % **:The Wyss Zurich Translational Center (Wyss Zurich) is a joint accelerator of the ETH Zurich and the University of Zurich, which was made possible by a generous donation from the Swiss entrepreneur and philanthropist Dr. hc. mult. Hansjörg Wyss. The mission of Wyss Zurich is to drive the clinical translation and technology transfer of outstanding scientific discoveries into new therapies for patients and breakthrough innovations in the emerging fields of Regenerative Medicine and Robotics, and to promote hybrid technologies in these fields. Wyss Zurich brings together some of the world's leading experts to form multidisciplinary teams, pooling their knowledge and expertise.

The project Recolony is focused on the development of a bacteria-based therapy for colorectal cancer that primarily consists of selected bacteria of the gut microbiota. These bacteria have an enormous influence on the immune system and are able to provoke and enhance an immune reaction against cancer. The bacteria will be orally applied in gastro-resistant capsules with colonic release. With this approach, Recolony aims to develop a new class of drugs for the treatment and prevention of cancer.

**Your responsibilities**:

- Development of bioinformatics tools based on human metagenomics and metabolomics datasets.
- Analysis of high throughput metagenomic and metatranscriptomic datasets from mice and human samples to analyze the gut microbiome, microbial-derived metabolites and differentially expressed genes
- Organization of collaborations with external research groups and experts in the field of bioinformatics, data analysis and machine learning.
- Setting up and curating the data infrastructure
- Investigate and keep track with state of the art technologies and tools for developing innovative data analysis strategies

**Your profile**:

- PhD related to bioinformatics
- More than 5 years' experience using bioinformatic tools
- Experience with the analysis of human and murine microbiome and multi-omics
- Experience developing new bioinformatics tools
- Good knowledge of the human microbiome
- Dynamic, team player and good communication and organizational skills
- High proficiency in English in written and spoken form

**What we offer**: This is a unique opportunity to join a young, dynamic and growing start-up team developing tomorrow's treatment against cancer. You will benefit from an inspiring and socially relevant environment.

**Place of work**: Weinbergstrasse, Zürich, Switzerland