Rna Biologist

vor 2 Wochen

Basel, Schweiz GITR Vollzeit

**EINFÜHRUNG**:
As a preferred supplier for Roche Basel, we are looking for an individual as

**RNA biologist - Bioformatician**:
contract for 18 months, with possible extension. The earliest start date is within 3 months.

**AUFGABENBESCHREIBUNG**:

- You bring deep scientific RNA and computational biology expertise as a key member of project teams.
- You develop in silico and/or wet lab technologies to design, screen and analyze genetically encoded transgenes with various modes of actions, such as splice modification, RNA knockdown, RNA and DNA editing, and tunable transgene expression.
- You facilitate our understanding of RNA (sequence and structure-based) as a target and as a therapeutic modality (shRNA, gRNA, ribozymes, etc) for viral and non-viral gene therapies.
- You generate ideas for innovative ways to modulate gene expression, as well as ideas for testing novel therapeutic mechanisms.
- You develop nurturing trustful relationships and effective collaboration with internal and external partners
- You have strong oral and written communication skills, and are proficient in working with cross-functional and multidisciplinary teams

**ERFORDERLICHES PROFIL**:

- PhD in molecular biology, genetics/genomics, computational biology, or related fields.
- Deep expertise in RNA biology and/or synthetic biology, ideally in the field of gene therapy and RNA therapeutics.
- Strong experience with the in silico design of genetic elements and expression cassettes, coupled to bioinformatics analysis of high-throughput screening and NGS datasets.**:

- A proven scientific-track record through impactful publications in relevant fields, patents, or substantial contributions to drug development programs
- Fluent in English - verbal and written
- Proficiency in using Python and R/Bioconductor
- Experience in bash scripting and working in Linux and HPC environment
- Proficiency in data analysis and machine learning techniques (clustering, generalized linear models, data visualization, data mining and reporting, generative AI)

**Application process**:
Interested? You can find more information here:

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