PhD Student In Engineering Organs-on-Chip For Lymphatic–Vascular Studies
Vor 2 Tagen
PhD student in Engineering Organs-on-Chip for Lymphatic–Vascular Studies (100%) myScience PhD-Position in Engineering Organs-on-Chip an der Universität Bern. Eine spannende Gelegenheit für innovative Forschung. Aufgaben Entwicklung von Organ-on-Chip-Systemen zur Untersuchung von Lymphgefäßen. Gestaltung und Optimierung mikrofluidischer Chips für biologische Anwendungen. Zusammenarbeit mit führenden Experten und Präsentation von Ergebnissen. Fähigkeiten M.Sc. In Maschinenbau, Biomedizintechnik oder verwandtem Bereich erforderlich. Starke Kenntnisse in Mikrofluidik und Zellkulturtechniken. Erfahrung in CAD-Design und Programmierkenntnisse in Python. Description Model development: Collaborate with research partners in Bern and Zurich to develop multi-compartments OOC systems integrating blood and lymphatic vasculature with key mechanical cues of the lung microenvironment Characterization: Design chips based on microfluidic and physical principles, fabricate & optimize using state-of-the-art microfabrication techniques and characterize chip performance (fluidics, mechanics, and reproducibility). Method development: Design and implement specific functional read-outs and quantitative assays to assess vascular-lymphatic interactions. Collaboration & dissemination: work closely with research partners, contribute to publications and present results at international conferences Requirements MSc in Mechanical Engineering, Biomedical Engineering, Microsystem Engineering or a related field Scientific Expertise & Technical Skills: Microfluidics: Strong theoretical and practical understanding of fluid dynamics, fluidic circuit design, and numerical simulation (e.g., COMSOL Multiphysics or ANSYS) and experience in designing, optimizing and validating microfluidic systems for biological applications Microfabrication & CAD: Strong engineering intuition and hands-on experience in developing and prototyping novel microfluidic systems (e.g., soft lithography, 3D printing) with experience in CAD-based device design and experimental validation Cell culture: Practical experience with cell culture in microfluidic systems, including co-culture approaches, and skilled in fluorescence microscopy and image analysis for functional read-outs of microphysiological systems Software: Proficiency in Python, MATLAB, or R for data analysis, and automation of experimental workflows Communications: Excellent oral and written communication skills in English Personal skills: Creative, organized, self-motivated & able to work both independently & within a multidisciplinary team We offer A stimulating interdisciplinary research environment linking bioengineering, cell biology and translational medicine Access to state-of-the-art microfluidic, organs-on-chip and imaging facilities Opportunities to collaborate with leading experts in vascular and lymphatic biology and COPD The successful PhD candidate will be enrolled in the Graduate School of Cellular and Biomedical Sciences (GCB) Salary according to the SNSF regulations A vibrant research setting in Bern, Switzerland’s capital, surrounded by the Aare river and the Bernese Alps The review of applications will start on December 1st, 2025. The position will remain open until it is filled. Please enable JavaScript to read the address. Web www.artorg.unibe.ch/research/ooc/index_eng.html In your application, please refer to myScience.ch and reference JobID68726.
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