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    Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche,...

Neuroscience Researcher

vor 1 Woche


Basel, Basel-Stadt, Schweiz F. Hoffmann-La Roche Gruppe Vollzeit

We are seeking a highly accomplished Neuroscience Researcher to join our Pharmaceutical Research and Early Development (pRED) organization.

About the Team

In this role, you will be part of a dynamic and interdisciplinary team that works together to transform science into medicines.

The Job Responsibilities
  • Design, execute, and analyze complex experimental models such as human organoid systems and human T cell functional assays to evaluate and validate mechanisms of action and potency of therapeutic compounds.

  • Lead pharmacology studies for compound characterization in neuroinflammatory and humanized in vivo models.

  • Collaborate with experts in immunology and neuroscience to identify new targets and clinically relevant pharmacodynamic biomarkers for neurodegenerative disorders.

  • Present data at project team, departmental, and governance meetings and mentor research associates and interns working in neuroimmunology.

Requirements
  • PhD in neuroscience/neuroimmunology, immunology, or other relevant discipline with minimum 4 years of relevant research experience in an academic setting and/or pharmaceutical industry/biotech sector.

  • In-depth knowledge of human and translational immunology, particularly B- and T cell biology, is a prerequisite, ideally experienced in human functional assays, multiomic based techniques, and analysis such as multiparameter flow cytometry, spatial tissue profiling/high content imaging, and/or immune repertoire.

  • Certification for performing in vivo animal experiments required. Expertise in in vivo animal dosing, perfusion, tissue collection, and preparation for histology, biochemical, and immunoassays.