Biotechnology Process Manager

Vor 2 Tagen


Schlieren, Zürich, Schweiz DINAMIQS Vollzeit

Siegfried DINAMIQS is a leading Contract Development and Manufacturing Organization (CDMO) in Switzerland, specializing in the manufacturing of viral vector gene therapies.

As a GMP Upstream Process Supervisor at DINAMIQS, you will have the opportunity to contribute to the development and implementation of cutting-edge process technologies and innovative solutions for our clients.

The role encompasses a diverse range of responsibilities:

  • Perform GMP Upstream operations, including mammalian cell culture, bioreactor management, and aseptic techniques for cell line handling.
  • Manage buffer and media preparation, powders, and liquids for internal supply, ensuring compliance with GMP standards.
  • Handle single-use technologies, including materials management, closed systems, and aseptic connectors, welding, and sealing.
  • Contribute to technology transfer and scale-up processes as needed.
  • Prepare, review, and manage GMP documentation, including manufacturing batch records, SOPs, and risk analyses, with an emphasis on electronic batch records and paperless environments.
  • Troubleshoot and resolve upstream manufacturing issues, conduct root cause analysis, and plan sector activities effectively.
  • Adapt to new technologies and implement innovative methods to enhance efficiency and production effectiveness.
  • Manage timelines and resources to meet company milestones, while providing training and guidance to staff on operational and compliance procedures.

To succeed in this role, you will require:

  • A degree in biotechnology, bioprocess engineering, or a related field.
  • 3-5 years of experience in pilot or commercial production of biotechnological products in the USP sector; experience with Advanced Therapies Medicinal Products is a plus.
  • Familiarity with QbD, cGMP, and commercial manufacturing requirements; experience in process and equipment qualification is desirable.
  • Proficient in Sartorius BioPat MFCS software, SCADA interfaces, and Microsoft Office Suite.
  • Experience in equipment and process qualification and validation from a production perspective.
  • Fluent in English; German is a plus.

You will work in a dynamic environment where you can develop your skills and expertise. As a valued member of our team, you will enjoy a competitive compensation package and benefits that promote work-life balance and employee well-being.



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