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Microscopy Image Analysis Expert

vor 2 Monaten


Basel, Basel-Stadt, Schweiz Roche Vollzeit
About the Role

We are seeking a highly skilled Microscopy Image Analysis Expert to join our team in Lead Discovery, a department within Small Molecule Research at Roche. As a key member of our research team, you will play a critical role in advancing our understanding of drug targets and mechanisms of action in targeted and phenotypic screening approaches.

Key Responsibilities
  • Design, implement, and execute image and data analysis strategies at scale for high-content imaging using cellular models (2D, 3D, organoids) by both segmentation/feature extraction and machine learning-based processes, data condensation, and data visualization.
  • Implement cutting-edge image analysis frameworks and QC standards to uncover complex patterns and extract relevant information from high-content imaging and screening datasets while closely working together with colleagues from the Assay Development and High Throughput Screening & Profiling teams.
  • Own the business process and solution for new data workflows around high-content screening and act as the key connector between the research teams in Lead Discovery and colleagues from the pRED Data & Analytics department.
  • Collaborate with multidisciplinary matrix teams and as an individual contributor working across pRED, internal stakeholders, and external vendors.
Requirements
  • A track record in microscopy image analysis and a solid understanding of cellular biology and drug discovery principles.
  • Experience in omics data analysis is beneficial, but not essential.
  • Strong programming skills in languages such as Python, R, or others, experience with relevant image analysis software tools such as CellProfiler, Imagence, ImageJ, FiJI, or others, as well as hands-on experience with popular deep learning frameworks (e.g., PyTorch, TensorFlow, Keras, Transformers).
  • Ability to communicate in a clear and concise manner and manage stakeholders efficiently in a matrix team, including technical and non-technical stakeholders.
About Roche

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity, and diversity. We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.