Research Scientist, Immunology

Vor 7 Tagen


Basel, Basel-Stadt, Schweiz BIIE Vollzeit
Job Summary

We are seeking a highly motivated Research Associate to join our team at the Botnar Institute of Immune Engineering (BIIE). The successful candidate will have a strong background in molecular biology and experimental immunology, with experience in high-dimensional flow cytometry and immune receptor repertoire sequencing library preparation.

Key Responsibilities
  • Design and optimize spectral flow cytometry panels for isolating and studying immune cells
  • Develop and optimize protocols for single-cell and bulk immune receptor repertoire sequencing
  • Prepare the NGS library and analyze the sequencing data
  • Produce and characterize monoclonal antibodies using biochemical and biophysical methods
  • Collaborate with cross-functional teams to establish and optimize automation
  • Analyze and interpret experimental data, maintaining detailed records of experiments and outcomes
  • Contribute to the development of new technologies and methodologies to improve high-throughput protein expression workflows
  • Prepare technical reports, summaries, protocols, and quantitative analyses
  • Present findings to team members and contribute to scientific discussions within the group
Requirements
  • Bachelor's or Master's degree in Immunology, Molecular Biology, Biochemistry, Chemical Engineering, or related field
  • Experience with flow cytometry and cell sorting
  • Familiarity with molecular biology techniques, such as PCR, cloning, and vector construction
  • Experience in monoclonal antibody production protein expression, purification, and characterization
  • Strong organizational skills with the ability to manage multiple projects simultaneously
  • Excellent problem-solving abilities and attention to detail
  • Effective communication skills, both written and verbal
  • Ability to work both independently and collaboratively in a team-oriented environment
About the Botnar Institute of Immune Engineering

The Botnar Institute of Immune Engineering (BIIE) is a newly founded non-profit research organization aiming to become a world leading research institute for the advanced study of immunological systems with a mission to develop translational solutions for the diagnosis, treatment and prevention of disease.

The scientific foundation of the BIIE is based on the intersection of three interdisciplinary subdomains: (i) systems immunology, (ii) synthetic immunology and (iii) computational immunology. The BIIE will serve as a hub for multidisciplinary science, by uniting people with diverse expertise in immunology, biomedicine, bioengineering, systems and synthetic biology, computational biology, artificial intelligence and machine learning.



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