Biopharmaceutical Research Associate

vor 3 Wochen


Basel, Basel-Stadt, Schweiz Roche Vollzeit
Job Title: Scientist in Biopharmaceutics

At Roche, we strive to deliver medical solutions that make a meaningful difference in patients' lives. We're seeking a highly motivated Scientist in Biopharmaceutics to join our Biopharmaceutics Team in Synthetic Molecules Drug Product Development. As a key member of our team, you will collaborate with experts across functions to develop advanced biopharmaceutics approaches and contribute to the formulation of innovative oral drug products.

Responsibilities:
  1. Apply state-of-the-art biopharmaceutics in vitro methods to generate mechanistic understanding of in vivo drug product performance.
  2. Develop and apply physiologically-based biopharmaceutics models to predict in vivo performance of oral formulations and other routes of administration.
  3. Collaborate with cross-functional teams to work on formulation development, drug substance and drug product analytics, DMPK, clinical pharmacology, modeling & simulation, regulatory, and SM research.
  4. Author and review technical reports, patent applications, and parts of regulatory documents to support filings.
  5. Collaborate with distinguished scientists in academia to strive for excellence in biopharmaceutics and develop new advanced technologies for absorption prediction.
Requirements:
  1. Hold an advanced degree in biopharmaceutics, pharmaceutical technology, or a related field, or have > 5 years of relevant experience in biopharmaceutics.
  2. Additional experience in drug product development of oral dosage forms is an advantage.
  3. Significant experience with state-of-the-art biopharmaceutics in vitro methods for oral DP performance testing.
  4. Relevant hands-on experience with physiologically-based biopharmaceutics modeling software Gastroplus/DDDPlus, Simcyp/SIVA.
  5. Capability to strive for excellent results and implement innovative solutions with a high level of motivation.
  6. Ability to interact effectively with people, strong commitment to teamwork.
  7. Will to work in a highly dynamic environment where you can bring in your creativity and continuously develop your scientific knowledge.
  8. Good communication skills with proficiency in German or English.


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