PhD Student Position in Retinal Research

vor 3 Wochen


Bern, Bern, Schweiz Universität Bern Vollzeit
Research Project Overview
The Department of Ophthalmology at the Universität Bern is seeking a highly motivated PhD student to join the research group Retinal Remodeling. The project focuses on the employment of Müller cells as potential candidates for replacing degenerated photoreceptors in the retina. The research aims to investigate the active modulation of Müller cell transition as a pivotal process during degeneration/regeneration and the treatment of chronic gliosis in mice.

Key Responsibilities
The PhD student will conduct pathway analysis in animal models with retinal degeneration, investigate cell type-associated differential gene expression, and perform pharmacological treatment and/or gene editing in regard to the identified pathways. The experimental spectrum will include classic methods in molecular and cell biology, as well as in vivo experiments using mice and zebrafish, and iPSC-derived or other cell-based systems. Bioinformatic evaluation of the data in collaboration with computer scientists will also be a key aspect of the project.

Requirements
The ideal candidate should hold a master's degree in biology, biomedical sciences, or related fields, with background knowledge in neurobiology and/or cell biology. Expertise in working with small animal models and bioinformatics would be advantageous. The successful candidate will be a highly motivated, interactive, and team-oriented individual with a high degree of self-initiative and inventiveness.

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