Research Associate, Biomarker Discovery

Vor 6 Tagen

Basel, Basel-Stadt, Schweiz Roche Vollzeit
Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people's varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.

That's what makes us Roche.

In Roche's Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world's toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

360 Labs Initiative at a Glance

The 360 Labs are a new capability that is currently being built up within the Pharmaceutical Research and Early Development organization (pRED). The primary mission of this effort is to provide greater access and support for the use of cutting-edge biomedical research technologies by scientists across our discovery portfolio.

The 360 Labs will deliver core scientific technologies, expertise and enabling activities, as well as facilitate knowledge sharing in close collaboration with our therapeutic areas and functions. Our ambition is to bring to life a thriving workplace environment, where your collaborative mindset is as valued as your professional expertise. Our goal is to act as an highly integrated ecosystem, supporting research and development, working collaboratively, and focused on fostering excellence and sustainability. Together, these efforts will serve to increase the speed, enhance the robustness and improve the sustainability of our exploratory research and early discovery activities.

The Opportunity

The Proteomics & Metabolomics Technology Platform in the 360 Labs Initiative is seeking an experienced, highly motivated, collaborative, and customer-centric lab-based professional with a focus on supporting investigative biomarker discovery efforts. The successful candidate will have a robust background in the life sciences and proficiency in implementing scalable targeted, high-plex, and untargeted protein assays. You will work with a sense of urgency as a part of a matrix team, interacting with colleagues within the Proteomics & Metabolomics Technology Platform to implement and execute experimental paradigms to advance biomarker identification and validation efforts. You will also participate in the continued evolution of the Proteomics & Metabolomics Technology Platform within the pRED organization.

Your Role and Responsibilities

- You will implement and execute both targeted (mid- and high-plex) and untargeted protein assays to enable investigative biomarker discovery studies in liquid biopsies, in vitro model systems and tissues;

- You will support multiple collaborations across therapeutic disease areas by generating, and analyzing biomarker discovery and validation experiments, contribute to the delivery of project reports, and engage with stakeholders to present and discuss findings in a dynamic and flexible manner;

- You will work collaboratively with your colleagues to contribute to general laboratory operations within the Proteomics & Metabolomics Technology Platform; including instrument maintenance, experimental troubleshooting, as well as the evaluation of new technologies;

- You embrace a continuous learning mindset by actively engaging with the scientific literature to stay abreast of emergent technologies/approaches in the biomarker discovery field.

Who you are

- You have a BS or MS degree in biochemistry, chemistry or a related field, with experience in the discovery and/or validation of biomarkers, preferably within either the biotechnology or pharmaceutical industry;

- You have proven hands-on expertise in the implementation and execution of various biochemical sample preparation workflows. You also demonstrate high competency in the operation of LC-MS systems and are familiar with targeted and untargeted workflows. Familiarity with non-MS based technologies (e.g. NULISA, Olink) will be considered a plus;

- You are familiar with the processing, analysis and interpretation of MS- and ideally also non-MS-based datastreams.

In addition to your scientific expertise and critical technical skills we are looking for candidates who are:

- Customer-focused with a drive for growth and a questioning mindset. Skilled in creative problem-solving, organization, and implementing innovative ideas efficiently in a fast-paced research context;

- Excellent communicators with a high fluency in English, a desire to continuously build a personal network and the ability to thrive in a dynamic, inclusive environment which gives you full accountability for your own contributions and development.

Your Location

This position is based in Basel

Our commitment

Roche commits to recognizing talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career.

We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

Roche is an Equal Opportunity Employer.

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