Discovery Scientist in Cardiovascular

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed. pRED Cardiovascular & Metabolism, Immunology (CMI), located in Basel, Switzerland, focuses on the discovery and early development of innovative treatments for specific diseases that affect the lives of millions. In the cardiovascular and metabolism area, we are developing cutting-edge therapies to treat metabolic diseases. As a member of the metabolism group, you will be part of an international group that includes scientists and clinicians who are developing medicines for the future. We are seeking for our Cardiovascular and Metabolic Diseases (CVM) department an experienced scientist with a strong industry background and a proven track record in the execution of preclinical projects in the area of Metabolic Diseases and Immunology. The opportunity In this role, you will design and execute experiments and lead projects to evaluate the efficacy and safety of novel therapeutic candidates. Key responsibilities: - Champion research projects from target ideation and validation, to entry into clinical development for both small- and large-molecule modalities. - Lead the positioning and prioritization of novel metabolic and immunological targets, integrating disease biology, translational biomarkers, and therapeutic modality selection to align with Roche’s CVM pipeline. - Demonstrate deep understanding of the science and create solid plans to collaboratively design, execute, and interpret complex preclinical experimental studies for the validation and characterization of targets or therapeutic agents - Direct, execute, and benchmark novel experiments, work together hand in hand with associates, and transfer standardized assays to associates - Act as a resource in project teams, and demonstrate clear and professional verbal and written communication Who You Are You’re someone who wants to influence your own development. You are looking for a company where you receive the opportunity to pursue your interests across functions and geographies. Working in a multicultural environment motivates you. As a fast learner you actively drive the quality of the requirements. - You possess a PhD degree in Life Sciences (muscle-/adipose-physiology, neuroscience, or metabolism), or a closely related discipline; and have >10 years of research and project leadership experience in the pharmaceutical industry. - Significant scientific accomplishments and successful collaborations documented by publications in high-impact journals - Ability to effectively present scientific data and concepts to colleagues, teams, and management is essential - Skillfully able to interact effectively with people, both internally and externally - Vigorous “can do” mentality to succeed in a dynamic and highly collaborative research team Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.