Principal Scientist

vor 2 Wochen

Basel, Schweiz Novartis Vollzeit

6500 That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.
At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. In 2020, we touched >700 million patients with our products. How can we continue to advance our science to help even more patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks.
At NIBR, we are at the core of Novartis’ purpose, designing and making new molecules for treating patients. We are looking for a highly motivated, passionate researcher with a strong scientific background in chemistry or related life science disciplines, a curious mind-set, and cultural agility to invent innovative medicines and advance the frontiers of drug discovery. Join us and help reimagine medicine
The NIBR RNAi Initiative is seeking a passionate, creative PhD level scientist to oversee our RNA synthesis team in Basel. You will work highly collaboratively in a multidisciplinary environment at the interface between research and development to discover and develop novel siRNA therapies for high unmet medical needs.

**Responsibilities**:

- Build and maintain a state-of-the-art oligonucleotide synthesis facility, diligently managing capital expense and consumables budgets
- Lead a team of scientists dedicated to oligonucleotide synthesis, purification, analytics and formulation from small to medium scale (nmol to mmol)
- Together with synthetic chemists and the project teams, conceive, implement and explore innovative siRNA chemistries to address key scientific questions and ensure their smooth transition to development
- Document and communicate results and scientific findings to internal and external audiences, in patent filings or scientific publications
- Support and develop team members by sharing your know-how and hands-on experience across your work environment

**Commitment to Diversity & Inclusion**:

- Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._

**Minimum requirements**

What you will bring to the role
- A PhD degree with a focus on the synthetic chemistry of oligonucleotides
- Demonstrated practical knowledge in oligonucleotide synthesis and downstream processing
- A track record of people leadership and development skills
- Ability to champion and advance creative concepts in a global team setting
- Innovative and independent problem-solving skills
- Ability to handle multiple tasks effectively, yet to prioritize and focus as needed
- Excellent oral and written communication skills

Why Novartis?
769 million lives were touched by Novartis medicines in 2020, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.
We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.
We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying
Imagine what you could do here at Novartis

Join our Novartis Network:
**Division**

Novartis Institutes for BioMedical Research

**Business Unit**

BIOLOGICS NIBR

**Country**

Switzerland

**Work Location**

Basel

**Company/Legal Entity**

Novartis Pharma AG

**Functional Area**

Research & Development

**Job Type**

Full Time

**Employment Type**

Regular

**Shift Work**

No

**Early Talent**

No

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