Bioinformatician / Computational Biologist

vor 3 Wochen

Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel Vollzeit

The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated **Bioinformatician / Computational Biologist** to analyse single cell genomics data in support of IOB’s therapy development efforts.

IOB is a research institute associated with the University of Basel which combines basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded.

IOB uses state of the art single cell genomics and epigenomics techniques to both understand vision and to test therapies aimed to restore vision. In your role, you will utilise your expertise to collaborate with our molecular research teams across the institute.

**Your responsibilities**
- Analyse genomics data including single cell RNA and ATAC sequencing
- Create cell type atlases and leverage them to answer biological research questions
- Support tissue engineering and therapeutic efforts by characterising intra/intercellular signalling pathways
- Compare diseased or engineered cell types to their healthy normal equivalents
- Organise sequencing data and maintain metadata information
- Participate in the development of pipelines to automate commonly used workflows
- Communicate clearly with biologists and bioinformaticians to identify objectives and convey results

**Requirements**:

- PhD in bioinformatics, computational biology or a related quantitative discipline
- Minimum 3 years’ experience in next-generation sequencing data analysis, single cell experience preferred
- Expertise in Python, competency in R, and fluency in Unix/Linux
- Experience with workflow management (Snakemake) and high performance or cloud computing
- In depth knowledge of common sequencing technologies
- Experience deciphering or employing intra
- or intercellular signalling pathways is desirable
- Excellent written and verbal communication skills in English

**We offer**
- Highly competitive conditions in a dynamic and international research community in Basel
- IOB is an equal-opportunity employer with family-friendly work policies

**Application / Contact**

IOB - Institute of Molecular and Clinical Ophthalmology Basel
Sandro Crameri
Head of Human Resources
: +41 79 511 26 54

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