Rna Biologist/bioinformatician
vor 2 Wochen
**RNA Biologist/Bioinformatician**
The focus of the position is to build and develop novel therapeutic approaches in the gene therapy space by using high-throughput and next generation sequencing (NGS) methods.
**Responsibilities**:
- You bring deep scientific RNA and computational biology expertise as a key member of project teams.
- You develop in silico and/or wet lab technologies to design, screen and analyze genetically encoded transgenes with various modes of actions, such as splice modification, RNA knockdown, RNA and DNA editing, and tunable transgene expression.
- You facilitate our understanding of RNA (sequence and structure-based) as a target and as a therapeutic modality (shRNA, gRNA, ribozymes, etc) for viral and non-viral gene therapies.
- You generate ideas for innovative ways to modulate gene expression, as well as ideas for testing novel therapeutic mechanisms.
- You develop nurturing trustful relationships and effective collaboration with internal and external partners
- You have strong oral and written communication skills, and are proficient in working with cross-functional and multidisciplinary teams
**Requirements**:
- PhD in molecular biology, genetics/genomics, computational biology, or related fields.
- Deep expertise in RNA biology and/or synthetic biology, ideally in the field of gene therapy and RNA therapeutics.
- trong experience with the in silico design of genetic elements and expression cassettes, coupled to bioinformatics analysis of high-throughput screening and NGS datasets.
- A proven scientific-track record through impactful publications in relevant fields, patents, or substantial contributions to drug development programs
- Proficiency in using Python and R/Bioconductor
- Experience in bash scripting and working in Linux and HPC environment
- Proficiency in data analysis and machine learning techniques (clustering, generalized linear models, data visualization, data mining and reporting, generative AI)
Sounds like a great job?
-
Bioinformatician / Computational Biologist
Vor 2 Tagen
Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel VollzeitThe Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated **Bioinformatician / Computational Biologist** to analyse single cell genomics data in support of IOB’s therapy development efforts. IOB is a research institute associated with the University of Basel which combines basic and clinical research. Its mission is...
-
Bioinformatician 100%
Gefunden in: beBee S CH - vor 3 Wochen
CH-4051 Basel Universität Basel VollzeitBioinformatician 100% The Bioinformatics Core Facility at the University Basel is seeking a Ph.D. level bioinformatician. The facility is a centralized resource of expertise for the analysis and visualization of large-scale biological datasets, available to researchers at the Department of Biomedicine (DBM) and the Biozentrum (BZ).The position is initially...
-
External Innovation Lead/Manager RNA Therapeutics
Gefunden in: Talent CH C2 - vor 1 Woche
Basel, Schweiz Roche VollzeitThe Position In Roche´s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility...
-
Laboratory Technician
Vor 3 Tagen
Basel, Schweiz Universität Basel VollzeitThe research groups of Visceral Surgery and Precision Medicine (Dr. Salvatore Piscuoglio), Translational Genitourinary Cancer Research (Dr. Clémentine Le Magnen) and Brain Tumor Immunotherapy (Prof. Gregor Hutter) are based at the Department of Biomedicine, Basel, Switzerland. Our groups are seeking a highly motivated Laboratory Technician in Molecular...
-
Discovery Postdoc
Gefunden in: beBee jobs CH - vor 1 Woche
Basel, Basel-Stadt, Schweiz Novartis VollzeitDiscovery Postdoc - Data ScienceSwitzerlandAbout the roleWe are seeking to hire a highly motivated discovery postdoc with a background in data science, to lead a research project investigating spatial and single cell expression in liver disease patient samples.You will have the opportunity to work in a matrix team consisting of data analysts, sequencing...
-
Associate Bioinformatics Data Scientist
Vor 3 Tagen
Basel, Schweiz Novartis Vollzeit250! The number of genomics research projects that are waiting for your data analysis expertise every year. Your work will be important towards faster discovery and development of next generation breakthrough therapies for unmet medical need. - The Autoimmunity, Transplantation and Inflammation (ATI) Disease Area at the Novartis Institutes for BioMedical...