Associate Principal Scientist Mrna Lnp

vor 2 Wochen


Basel, Schweiz Lonza Vollzeit

Switzerland, BaselToday, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

**Key responsibilities**:

- Representation: act as a deputy of the team manager when needed and support the process development management
- Leadership: provide strong scientific, technical and regulatory leadership at project level. Lead individual scientists and lab technicians on complex projects
- Projects: lead multi-disciplinary matrix teams on complex projects in the area of scientific expertise. Lead problem solving and lessons learned activities
- Scientific tasks: design advanced experimental plans and data analysis methods, write and review high quality reports
- Customer interactions: develop strong customer relationships
- Training: lead training activities in the area of expertise
- Provide solutions to identified risks, issues, problems. Report issues in a timely fashion.
- Facilitate improvements to departmental business processes and contribute to the implementation of innovative technologies
- Demonstrate flexibility to support other activities within the department
- Proactive approach to own continuous professional development

**Key requirements**:

- Degree in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences or related field
- Accountable of research on LNP/mRNA processes for pharmaceutical formulations
- In-depth knowledge with liposome/lipid nanoparticle formulations development
- Experience with analyzing data derived from process development, high-throughput screening and/or analytical characterization techniques (UV-Vis, fluorescence, SLS/DLS, particle characterization, FTIR, IR, DSC, chromatography, NMR or SAXS, etc)
- Broad & deep expert-level experience & understanding of TFF ideally adapted to LNP/mRNA LNPs
- Demonstrated ability to efficiently work in a fast paced and fluid environment, changes in priority and timeline restrictions
- Understanding of preparation, stabilization and process scale-up of LNPs formulations.
- Design DoE studies & high-throughput screen for lipid formulations
- Experience with analytical assays associated with LNP mixing technologies
- Knowledge of technology transfer and GMP manufacturing

Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

**Reference: R51550**:

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