Research Scientist
Vor 6 Tagen
PKS- Drug Disposition - Global Biotransformation - Regulatory Metabolite Identification and Outsourcing Excellence
- Do you want to be at the forefront of the fight against multiple diseases making an impactful contribution in bringing transformative therapies to patients and be part of Novartis’ mission to reimagine medicine to improve and extend people’s lives?- **Responsibilities**:
- Organize and prepare experimental protocols and study reports with upload of results to a centralized database
- Develop and perform assays to characterize the metabolism of small molecule as well as new modalities
- Assure quality standard guidelines and safe work practices are applied while working in the laboratories
**Commitment to Diversity & Inclusion**:
- Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._
**Minimum requirements**- Familiarity with in vitro systems (hepatocytes, microsomes, S9 fraction, recombinant enzymes) and in vivo bioanalyses
- Hands-on experience in operation, maintenance, and troubleshooting of state of the art high resolution UPLC-MS instruments
- Knowledge of safe handling practices and tracking of samples including radioactivity would be a plus
- Familiarity with mass spectrometer data interpretation for small molecule and or proteins
- Prior experience with radiolabeled compounds would be an asset
- Experience with radioactivity detection TopCount, Liquid Scintillation Counting (LSC) and Accelerated Mass Spectrometry (AMS) would be beneficial
- High interest in evaluating and implementing new technologies (Ion Mobility, LESA, MALDI etc.)
- Excellent oral and written communication skills
- Careful attention to detail, exceptional organizational skills and ability to multitask
- Strong and highly supportive team player, with aim to work in a highly collaborative environment
Basic Qualifications:
- Degree in Chemistry/Biochemistry/Biology/Pharmacology with research experience relevant to drug metabolism science
- MSc with 3 years, or BSc with 7 years of relevant experience
Why Novartis?
- 766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse,
- equitable and inclusive environment inspires new ways of working.
- We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we
- collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying
- Imagine what you could do here at Novartis**Division**
- NIBR**Business Unit**
- Translational Medicine**Country**
- Switzerland**Work Location**
- Basel**Company/Legal Entity**
- Novartis Pharma AG**Functional Area**
- Research & Development**Job Type**
- Full Time**Employment Type**
- Regular**Shift Work**
- No**Early Talent**
- No
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