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Associate Principal Scientist Nonclinical Dmpk
vor 1 Woche
Description
Debiopharm is an independent biopharmaceutical company based in Switzerland with an ongoing commitment to research in oncology and infectious diseases in order to improve patient outcomes and quality of life. Our main activities include drug development, drug manufacturing and digital health investment. Debiopharm International SA aims to develop innovative therapies that target high unmet medical needs. Our unique “development only” business model allows us to act as a bridge between disruptive discovery products and patient access in international markets. We first identify high-potential compounds for in-licensing, clinically demonstrate their safety and efficacy and then select large pharmaceutical commercialization partners to maximize patient access globally.
At Debiopharm you will be at the forefront of the fight against cancer and infectious diseases, and you will have the opportunity to work on new innovative medicines for patients. Efficiency is our mode of action, saving lives our collective target.
For our Nonclinical DMPK unit within the Translational Medicine organization based at our Headquarters in Lausanne, we are looking for a
Associate Principal Scientist, Nonclinical DMPK
A recognized expert in nonclinical DMPK, in this role, you will lead the nonclinical DMPK scientific strategy within cross-functional Oncology and Antibiotics projects to add value to, support, and accelerate the development of Debiopharm’s innovative therapeutics.
At Debiopharm you will be at the forefront of the fight against cancer and infectious diseases, and you will have the opportunity to work on new innovative medicines for patients. Efficacy is our mode of action, saving lives our collective target.
**Your responsibilities will be but not limited to**:
Design and implement the nonclinical DMPK strategy in drug discovery and drug development projects, including:
In vitro and in vivo studies to support Drug Development (regulatory and nonregulatory)
Modelling and simulation of nonclinical data to support human dose prediction
Manage finance, budget and timelines
Manage outsourced activities to an international network of CROs or through academic collaborations
Drive project strategy within multifunctional team
Prepare the nonclinical DMPK documentation to support regulatory activities and intellectual property protection
Participate in interactions with health authorities and external partners
Contribute and participate to scientific communications and events
As part of Debiopharm's model, contribute to in/out licensing activities and external grant-seeking
**Requirements**:
**Your profile**:
PhD, engineer degree or equivalent in pharmacokinetics, pharmacology, life sciences or other discipline relevant to nonclinical DMPK with at least 7 years experience in Translational Research and Drug Development in industry
Experience in drug development of biologics (namely, antibodies and ADCs)
In-depth understanding of bioanalysis, drug disposition, modeling and simulation, dose finding and drug-drug interaction risk at all stages of drug discovery and development
Knowledge of GLP and ICH guidelines, and of animal welfare regulations
Fluency in English (both oral and written)
Very good communication skills & influencing skills (oral and written)
Strong team player, looking to drive further projects and innovation
Strong organizational skills and project management experience
Team management and leadership experience is a plus
International, highly dynamic environment with a long term vision.
Cross-functional collaboration at the forefront of the most advanced scientific developments in oncology and anti-bacterial industry
Exposure to a wide variety of areas and functions within clinical development and the pharmaceutical industry
Participation in a company where innovation, people and entrepreneurship are the fundamental keys to success.
Proud to be an Equal-Pay certified, we ensure offering to all our employees the same opportunities
**Benefits**:
**Debiopharm offers employees**:
International, highly dynamic environment with a long term vision.
Cross-functional collaboration at the forefront of the most advanced scientific developments in oncology and anti-bacterial industry
Exposure to a wide variety of areas and functions within clinical development and the pharmaceutical industry
Participation in a company where innovation, people and entrepreneurship are the fundamental keys to success.
Proud to be an Equal-Pay certified, we ensure offering to all our employees the same opportunities
Submission of unsolicited resumes in advance of an agreement between the Human Resources Department and the external staffing agency or recruiter does not create any implied obligation on the part of Debiopharm.
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