Associate Principal Scientist Translational

vor 2 Monaten

Lausanne, Schweiz Debiopharm Vollzeit

Description

Debiopharm is an independent biopharmaceutical company based in Switzerland with an ongoing commitment to research in oncology and infectious diseases in order to improve patient outcomes and quality of life. Our main activities include drug development, drug manufacturing and digital health investment. Debiopharm International SA aims to develop innovative therapies that target high unmet medical needs. Our unique “development only” business model allows us to act as a bridge between disruptive discovery products and patient access in international markets. We first identify high-potential compounds for in-licensing, clinically demonstrate their safety and efficacy and then select large pharmaceutical commercialization partners to maximize patient access globally.

At Debiopharm you will be at the forefront of the fight against cancer and infectious diseases, and you will have the opportunity to work on new innovative medicines for patients. Efficiency is our mode of action, saving lives our collective target.

For our Research and Development Personalised Medincine organization based at our Headquarters in Lausanne, we are looking for an

Associate Principle Scientist Translational Medicine

In this newly created role, you will represent the Personalised Medicine Unit in assigned drug development programs and develop the predictive biomarker and the companion diagnostic strategies in accordance with project plans.

**Your responsibilities will be but not limited to**:
Actively participates in the drug development and, in particular, develop the Predictive Biomarker and the Companion Diagnostic strategies in assigned projects
Responsible for the Personalized Medicine portion of assigned clinical studies
Choose the best companion diagnostic strategies and implement them through establishing partnerships with diagnostic providers, in assigned projects
Can act as Translational Medicine leader on large projects including late-stage development strategy
Participates in the development of business strategy for the projects
Can lead large cross functional projects or collaboration (e.g. Partnering, Steering committee, etc.)
Develops strategies for a project within area of expertise & is accountable for success of such strategies
Develops and manages plans for Personalised Medicine pre-clinical studies and/or clinical activities according to GCPs and GCLPs and manage budget and timelines accordingly
Prioritizes and manages outsourcing activities to an international network of CROs (selec-tion and monitoring of CROs)
Provide intelligence on diagnostic products and emerging technologies in the area of per-sonalised medicine
Identify the intellectual property, inventions and innovation opportunities, and collaborates with legal department to feed DPI’s patent portfolio
Contribute to the preparation of documentations (e.g. IB, briefing books, informed con-sent forms and clinical protocols, SAP and CSR )
May participate in meetings with health authorities and health technology assessment (HTA) bodies
Provide support to other Departments of Debiopharm International S.A. (e.g. Clinical De-velopment, Regulatory Affairs,) and other affiliates of Debiopharm Groups such as Debiopharm Innovation Fund S.A
Contribute to in or out licensing activities
Evaluation of new external opportunities
Participation in due diligences
Participation in out-licensing activities
**Requirements**:
PhD with expertise in Molecular Biology and Biochemistry
At least 7 years of professional experience in Biotech/Pharmaceutical Industry
Experienced in Translational Research and drug development in industry
Expert scientific knowledge in oncology
Experience in companion diagnostic development
Ability to lead complex cross functional projects incorporating wide ranging areas of expertise, including regulatory aspects for diagnostic
Good knowledge of ICH and GCP guidelines
Fluent in English
Excellent communication skills (oral and written)
Team player, perseverant and able to promote innovation

**Benefits**:
**Debiopharm offers employees**:
International, highly dynamic environment with a long term vision.
Cross-functional collaboration at the forefront of the most advanced scientific developments in oncology and anti-bacterial industry
Exposure to a wide variety of areas and functions within clinical development and the pharmaceutical industry
Participation in a company where innovation, people and entrepreneurship are the fundamental keys to success
Proud to be an Equal-Pay certified, we ensure offering to all our employees the same opportunities

Submission of unsolicited resumes in advance of an agreement between the Human Resources Department and the external staffing agency or recruiter does not create any implied obligation on the part of Debiopharm.

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