Scientist - Gene Regulation (Sgr-ai)
vor 1 Monat
**The Company**
HAYA Therapeutics SA is a precision therapeutics company that discovers and develops innovative tissue
**About the job**
**Primary responsibilities**
- Evaluation of the therapeutic potential and efficacy of novel targets using _in vitro_ or _in vivo_ pathological models.
- Aim for rapid proof-of-concept, strategic triage of ideas, and quickly translating new approaches into company assets.
- Attend conferences and develop relationships with key opinion leaders.
- Generate, interpret, and present data to the R&D teams and senior managers.
- Maintain an up-to-date electronic notebook record of performed studies.
**Requirements**:
- Ph.D. in epigenetics/evolutionary biology/genome biology (or equivalent).
- Strong background, interest and demonstrated track record in gene transcription regulation, regulatory element evolution, functional genomics.
- Extensive hands-on experience in designing, performing, and analyzing a wide array of molecular biology assays including nucleic acid extraction from isolated cells and tissues, qRT-PCR, CRISPR assays, shRNA and siRNA transfection. The position is lab-based, expected to be **70% wet lab**, 30% experimental design and analysis.
- Proficiency with NGS technologies such as ChIP-seq, RNA-seq, PRO-seq, ATAC-seq and scRNA-seq.
- Experience in mammalian primary cell culture and general tissue culture techniques.
- Skills in bioinformatics and scripting for the analysis and interpretation of NGS assays are a plus.
**Location**: Lausanne, Switzerland
**Conditions of Employment**: Proof of Eligibility to work in Switzerland (Swiss work permit or Swiss / European citizenship)
Excellent salary and benefits package offered.
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