Research Associate Hit Characterization

Vor 3 Tagen


Schlieren, Schweiz CDR-Life AG Vollzeit

To expand the Hit characterization team within our Pharmacology group we are seeking a highly motivated and experienced:
**Research Associate Hit characterization (80-100%)**
- Characterization of antibody hits to generate first-in-class immuno-oncology drugs_

You will play an important role in the early characterization of antibody hits using various immunological and cell biological assays to support the lead selection process as part of CDR-Life’s pipeline of immunotherapies. You will work in a highly dynamic matrix environment in close collaboration with other members of the Pharmacology & Discovery group to drive scientific research and innovation.

**Key responsibilities**
- Design, conduct and analyze experiments to characterize antibody-derived molecules in cell-based assays (e.g. FACS binding studies, cytotoxicity and cytokine readouts) to allow selection of leads for further optimization
- Develop assays and implement tools to support hit characterization (e.g. cell line generation)
- Document and report the results to the team
- Work closely with other pharmacology team members as well as discovery group to support hit identification and lead selection
- Maintain and optimize mammalian cell culture processes and general laboratory infrastructure
- Analyze, interpret and present experimental results at internal meetings

**Qualifications**
- MSc, BSc or training as laboratory technician in Biology, Cell Biology, or equivalent degree in biological sciences
- 2+ years work experience within an industry setting is required
- Highly experienced in mammalian cell culture work conducting cell-based assays
- Hands-on experience with Flow Cytometry
- Experience with ELISA
- Well-organized with an independent and accurate working style
- Positive, reliable, open-minded, and flexible team player
- Fluency in English



  • Schlieren, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international partner, Roche Glycart AG based in Schlieren ZH, we are looking for a qualified and motivated **Biology Research Associate** for a contract of six months. Roche believes it is urgent to deliver medical solutions right now - even as they develop innovations for the future. They are passionate about transforming...

  • Research Associate

    vor 2 Wochen


    Schlieren, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international partner, Roche Diagnostics International Ltd. based in Schlieren, we are looking for a qualified and motivated **Research Associate** for 12 months with option for extension. The Zurich Roche Center of Excellence is active in the research and development of engineered therapeutic antibodies, with a focus on the fields...

  • Research Associate

    vor 7 Monaten


    Schlieren, Schweiz LimmaTech Biologics AG Vollzeit

    LimmaTech Biologics AG is a Swiss clinical stage biopharmaceutical company. We are advancing our proprietary vaccine pipeline to halt the increasing threat of global infections due to emerging antimicrobial resistance (AMR) and sexually transmitted diseases. Working at LimmaTech is a unique chance to be part of the development of life saving vaccines. To...


  • Schlieren, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international partner, Roche Diagnostics International Ltd. based in Rotkreuz, we are looking for an additional qualified **Junior Research Associate** for one year with option for extension. In this role, you will be working across two teams within two different laboratories. One team consists of 4 members and the second consists...

  • Research Associate

    Vor 3 Tagen


    Schlieren, Schweiz Virometix AG Vollzeit

    Virometix AG is a clinical stage biotechnology company developing new generation synthetic vaccines for the prevention and treatment of infectious diseases and cancer. Tasks - Conducting peptide synthesis, conjugations, and purification experiments - Maintaining accurate records of data and procedures - Presenting in team meetings and reporting of results -...


  • Schlieren, Schweiz CDR-Life AG Vollzeit

    Supporting in vitro-based characterization of first-in-class immuno-oncology drugs_ **Responsibilities include, but are not limited to**: - Develop, optimize and conduct cell-based assays focused on characterization of T cell engagers - Co-culture assays with primary cells/cancer cell lines - T-cell proliferation/activation - Cytotoxicity and cytokine...


  • Schlieren, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international partner, Roche Glycart AG based in Zürich Schlieren, we are looking for a qualified and motivated **Associate in** **Display Technologies** for 12 months with option for extension. In Roche´s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to...


  • Schlieren, Schweiz Global Personal Partner Vollzeit

    **EINFÜHRUNG**: Our profession and our passion "HR Management." Global Personal is an independent company of the Interiman Group SA with over 100 employees offering a complete range of human resources services at 21 locations in German-speaking Switzerland. For our client, an international orientated Pharma company in Schlieren (ZH) we are looking for a...


  • Schlieren, Schweiz Molecular Partners AG Vollzeit

    **General information**: **Reference **:2024-166 **Information about Molecular Partners AG**: **Position description**: **Position title**: Research Associate Cell Line Development **Job description**: We are seeking a skilled Research Associate to join our Cell Line Development team. This role will contribute technically and scientifically to the...


  • Schlieren, Schweiz GITR Vollzeit

    **EINFÜHRUNG**: As a preferred supplier for F. Hoffmann - La Roche Ltd. in Schlieren, we are looking for an individual as **Research Associate, Oncology Discovery**: with contract for 1 year. The earliest start date is within 2 months. **AUFGABENBESCHREIBUNG**: - Planning, conducting, analyzing and interpreting in vitro/ex vivo assays based on...

  • Research Associate

    vor 2 Wochen


    Schlieren, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international medical partner,** Roche Diagnostics Int Ltd. **based in Schlieren (Zurich), we are looking for a qualified and motivated **Research Associate** for 12 months with option for extension. **Tasks**: - Execute production of a variety of protein types, including therapeutic antibodies, in mammalian expression systems at...

  • Research Associate

    vor 2 Wochen


    Schlieren, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international partner, Roche Glycart AG based in Schlieren ZH, we are looking for a qualified and motivated **Research Associate** for one year with option for extension. **Tasks**: - Ordering and registration of DNA and proteins - Generation of long linear DNA fragments and/or plasmids - Sequence analysis and data handling -...

  • Research Associate

    vor 2 Wochen


    Schlieren, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international partner, Roche Diagnostics International Ltd. based in Schlieren, we are looking for a qualified and motivated **Research Associate** for 12 months with option for extension. **Tasks**: - Setting up and optimizing high throughput plasmid generation - Evaluation and optimization of existing workflows - Transfer of...

  • Research Associate

    vor 7 Monaten


    Schlieren, Schweiz Athebio AG Vollzeit

    Founded in late 2019, Athebio is a highly dynamic biotech startup developing advanced binding molecules for pharma partners based on Designed Ankyrin Repeat Proteins (DARPins). Do you want to grow with us? Do you bring a passion for life sciences, and are you eager to support the development of next-generation Athebody® DARPins? Are you equipped with a...


  • Schlieren, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international partner, Roche Diagnostics International Ltd. based in Schlieren, we are looking for a qualified and motivated **Research Associate** for 12 months with option for extension. **Tasks**: - Independent design and generation of vector constructs for transfection and/or transduction of different cell lines - Ensure...


  • Schlieren, Schweiz Biognosys AG Vollzeit

    DEPARTMENT: Operations COMPANY: Biognosys AG LOCATION: Wagistrasse 21 | 8952 Schlieren | Switzerland CONTACT: Arina Klein, (HR Specialist) | Telephone: +41 44 244 50 18 At Biognosys, we believe that deep proteome insights hold the key to breakthrough discoveries that transform science for better lives. With our versatile portfolio of next-generation...

  • Analytical Associate

    vor 23 Stunden


    Schlieren, Schweiz LimmaTech Biologics AG Vollzeit

    LimmaTech Biologics AG is a Swiss clinical stage biopharmaceutical company. We are advancing our proprietary vaccine pipeline to halt the increasing threat of global infections due to emerging antimicrobial resistance (AMR) and sexually transmitted diseases. Working at LimmaTech is a unique chance to be part of the development of life saving vaccines. Join...


  • Schlieren, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international partner, Roche Diagnostics International Ltd. based in Schlieren ZH, we are looking for a qualified and motivated **Logistical Lab Associate** for one year with option for extension. Roche Innovation Center Zurich is pRED’s Center of Excellence for Cancer Immunotherapy. It boasts a multinational team of some 185...


  • Schlieren, Schweiz LimmaTech Biologics AG Vollzeit

    LimmaTech Biologics AG is a clinical stage biopharmaceutical company active in the vaccine field. In collaboration with GlaxoSmithKline, LimmaTech develops new generations of bioconjugate vaccines against major bacterial diseases. Are you excited about the opportunity to contribute to the development of early-stage vaccines by running various biological...


  • Schlieren, Schweiz Molecular Partners AG Vollzeit

    **General information**: **Reference **:2024-168 **Information about Molecular Partners AG**: Molecular Partners AG is a clinical-stage biotech company pioneering the design and development of DARPin therapeutics for medical challenges other drug modalities cannot readily address. Founded in 2004 by a group of PhD students from the University of Zurich, we...