Lc-ms Biopharmaceuticals Scientist

vor 4 Wochen


CorsiersurVevey, Schweiz Merck KGaA Vollzeit

Work Your Magic with us

Ready to explore, break barriers, and discover more? We know you've got big plans '“ so do we Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

An exciting new opportunity has arisen at our State-Of-The-Art Biotech Development Facility in Switzerland.

**Your role**:
Reporting to Analytical Development Lab Manager in BDC Analytical Development and Innovation unit in the Global Analytical Development organization, this role represents an opportunity to significantly contribute to the startup of high-tech analytical laboratories in the BDC, by supporting the development and implementation of analytical assay for high throughout therapeutics proteins analytics and characterization.

Your key responsibilities in this role are:
Contribute to the startup of high-tech development analytical laboratories in the BDC as following:

- Conduct Mass spectrometry based analytical method development using our robotic platform
- Support the development & implementation of new assay including automatized ones, support the Analytical Operations and QC group for method transfer and troubleshooting. Evaluate results and report data, including trend analysis, as required. Contribute to the data review process according to the established standards requirements.
- Support the CMC project by providing analytical expertise and guidance In Coordination team meetings, be a key actor of the analytical strategy for CMC, influences and drive implementation of fit-for-purpose analytical solutions.
- Make use of automatized and digital systems in BDC to generate, document and report results.
- Provide input and identify problems with scientific experiments in related areas; contribute to laboratory investigations and troubleshooting; meet quality and safety standards.
- Impact the effectiveness of own work team through the quality and timeliness of the work produced, working to achieve objectives and meet deadlines.
- Manage own workload and expands technical and scientific contribution by exchanging ideas and information effectively in a concise and logical way and collaborating with colleagues. Engage and execute on training program, with focus on performance and personal development.

**Who you are:
- Graduate degree in Chemistry, Pharmacy, Biology, or Biotechnology or related field, and a t least two years of experience on antibody protein analytics using HPLC and HPLC-MS detection is a must
- Hands-on experience on proteomics especially for NBES, ADC, fusion protein, etc using HRMS, knowledge of Orbitrap platforms is a must
- Hands on experience on MAM data treatment software such as Genedata
- Knowledge of orthogonal techniques such as electrophoresis, ELISA (immunoassays), Digital PCR is a plus
- Experienced use of automated liquid handler is an asset
- Knowledge on international guidelines (e.g. ICH) for biopharmaceuticals; knowledge of Data generation, Data processing, Data Quality principles, Quality by Design (e.g., DoE)
- Preferred hands-on experience with laboratory information systems, digital tools and lean principles
- Highly motivated and self-driven, and multi-task to support department and business objectives
- Curiosity and open minded to new tools & technology English fluent, French is an asset

**What we offer**:We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress



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