Selection and Screening Head

vor 3 Wochen


Schlieren, Schweiz Molecular Partners AG Vollzeit

**General information**:
**Reference **:2023-144

**Information about Molecular Partners AG**:
Founded in 2004 by a group of PhD students as a spin-off from the University of Zurich, Molecular Partners AG is a thriving and steadily growing clinical stage biotech company located in Zurich-Schlieren (Switzerland) with 200 highly qualified employees.

In order to advance modern medicine and significantly improve the management of serious diseases, we have developed and successfully established a powerful new class of potent, specific and versatile small protein therapies, called DARPin therapeutics.

The highly dedicated, multi-disciplined team at MP is committed to developing breakthrough medicines for serious diseases.

**Position description**:
**Position title**:
Selection and Screening Head - Lead Generation (100%)

**Job description**:
This challenging and diverse position will include the following tasks and responsibilities:

- Supervision of the team performing ribosome display and phage display selections, as well as of the DARPin screening and formatting experts.
- Maintaining the DARPin leadership by integration of learnings for DARPin improvements into the design of the next generation DARPin libraries with superior properties.
- Supporting and guiding project teams with selection strategies, tailored to the needs of the targets and indications.
- Bring the screening technologies to the next level, by implementation of new technologies (automation, digital tools, etc.).
- Lead DARPin platform initiatives within/adjacent to our pipeline projects to evolve the DARPin scaffold to “teach DARPins new tricks.”

**Requirements**:
For this position, we are looking for an enthusiastic and highly skilled individual who features the following credentials:

- An agile and dedicated “driver” and team-player who is eager to help bring our DARPin generation platform to the next level.
- Scientist with a PhD in Biochemistry, structural biology, or related field with 10+ years in a biotech/pharma environment.
- Proven leadership skills, with successful supervision of a diverse group of lab technicians and scientists.
- Deep experience in the selection, screening, and characterization of antibody-based, peptide-based and/or alternative scaffold binders.
- Strong in identifying improvements in our lead generation process pipeline and able to quickly propose and execute remedies.
- Experience in the integration of digital tools (AI/machine learning) as well as in lab automation in the selection and screening process is considered a plus.

This position summary is not intended to be all inclusive. An employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

**Our offer**:

**Position location**:
**Job location**:
Switzerland, Zürich, Schlieren

**Preferred head hunter clause**:
Molecular Partners AG, Wagistrasse 14, CH-8952 Zurich-Schlieren, Switzerland.


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