Continuous Manufacturing Superuser
vor 2 Wochen
**Working with Us**
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Main Responsibilities include:
- Support the qualification of the new CDC (Continuous Direct Compression) unit including material handling and ancillary equipment.
- Highly knowledgeable about Continuous Tablet Compression equipment and it’s components. Including setup, operation, and routine maintenance of Loss In Weight powder feeders, inline blenders, tablet presses and their auxiliary equipment.
- Support scaling up processes from small scale to production scale, ensuring a smooth transition while maintaining product quality.
- Can diagnose and address equipment issues promptly, minimizing downtime and production interruptions.
- Expertise to make real-time adjustments to process parameters within qualified range to maintain product quality and yield.
- Actively identify opportunities for process optimization, including adjustments to improve tablet quality, reduce waste, and enhance efficiency.
- Via collaboration with DPD, MS&T and other functions, participate to the technology transfer of Drug Product from Drug Product Development (DPD) to Oral Solid Dosage (OSD) late stage and launch facility Boudry.
- Represent Manufacturing operations in manufacturing readiness meetings for new compounds.
- Provide training to operators, supervisors and junior staff, imparting expertise and best practices.
- Is the go-to expert for troubleshooting complex issues related to continuous direct compression.
- Utilize PAT tools, it’s data handling and techniques to monitor and control key process parameters in real-time.
- Ability to analyze manufacturing data and use statistical tools to identify trends, deviations, and areas for improvement.
- Participates in all manufacturing activities of assigned batches making sure that all activities are performed in accordance with approved SOPs and company policies.
- Responsible for contributing to and/or leading quality investigations, change controls and generation of SOPs and Cleaning Instructions.
- May represent Manufacturing Boudry as prime technical contact with regards to Continuous Manufacturing technology.
Position Requirements:
- Bachelor’s Degree in Engineering with a minimum of 5 years of experience in a cGMP Pharmaceutical manufacturing/technical environment or Bachelor’s Degree in Science with direct experience in Continuous Manufacturing.
- Minimum 5 years of experience in pharmaceutical formulation, process development, or manufacturing technology of small molecule oral solid dosage.
- Basic understanding of Near Infrared Spectroscopy.
- Basic understanding of Continuous Stirred Tank Reactor models.
- Advanced understanding of Loss In Weight feeder systems.
- Previous hands-on experience in Continuous Manufacturing is a must.
- Previous experience and/or proficient knowledge in Process Analytical Technology.
- General knowledge of Automation and Statistical Analysis.
- Demonstrated record of implementing creative solutions to overcome process-related obstacles.
- Strong interpersonal skills and the ability to work in a fast paced, multidisciplinary environment.
**Uniquely Interesting Work, Life-changing Careers**
**On-site Protocol**
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
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