Scientist / Senior Scientist in Cheminformatics

Na Roche, você pode-se apresentar como você mesmo, abraçado pelas qualidades únicas que traz. Nossa cultura incentiva a expressão pessoal, o diálogo aberto e as conexões genuínas, onde você é valorizado e respeitado por quem você é, e permitindo que você prospere tanto pessoal como profissionalmente. É assim que pretendemos prevenir, deter e curar doenças e garantir que todos tenham acesso aos cuidados de saúde hoje e nas gerações futuras. Junte-se à Roche, onde cada voz é importante.### A posiçãoWe are seeking a highly motivated Scientist / Senior Scientist in Cheminformatics to join our small-molecule team within the AI for Drug Discovery organization at Roche’s Computational Sciences Center of Excellence. As a core contributor addressing key drug discovery challenges at the intersection of AI and established computational technologies, you will develop and apply cheminformatics and computational approaches, implement robust scientific software, and analyze complex datasets to accelerate molecular design and hypothesis generation.In this role, you will operate at the interface between computational methods, AI models, and experimental workflows. Whether developing workflows to analyze biochemical data, enabling AI technologies, or independently creating scalable cheminformatics applications, your work will directly support the discovery of new therapeutic projects. You will collaborate closely with machine learning scientists, computational and medicinal chemists, and structural biologists to translate scientific needs into impactful computational solutions.### **The Opportunity*** Design, build, and maintain reliable cheminformatics pipelines and workflows that enable AI models, medicinal chemistry insights, and related structural biology tools.* Collaborate with cross-functional partners (ML scientists, experimentalists, chemists) to tackle critical challenges in small-molecule drug discovery.* Curate, integrate, and leverage diverse biochemical, biophysical, and chemical datasets to advance AI models, analyses, and discovery workflows.* Apply and refine best practices in data analysis, scientific software development, and algorithm design.* Contribute to the scientific community through documentation, internal communication, conference presentations, and written reports or publications.### **Who You Are*** You hold a PhD in a physical or quantitative discipline with 0–2 years of experience, or a BS/MS with 5+ years of relevant industry research experience.* You have a proven track record of innovating and delivering cheminformatics solutions, scientific software, and independent data analyses, demonstrated by substantial co-authorship on publications, internal reports, or conference presentations.* You are fluent in cheminformatics/modeling toolkits (e.g., RDKit, OpenEye), Python, and modern ML frameworks (e.g., PyTorch, scikit-learn).* You have deep experience with chemical datasets and concepts such as LBDD/SBDD and protein structures; knowledge of adjacent areas, such as Quantum Mechanics, is a plus.* You are an effective communicator who fosters team collaboration and can translate scientific ideas from non-data scientists into practical computational solutions. A public project portfolio (GitHub/GitLab) is a plus.#ComputationCoE #tech4lifeComputationalSciencesWhere pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Basel. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.### Quem nós somosUm futuro mais saudável nos leva a inovar. Juntos, mais de 100 mil funcionários em todo o mundo se dedicam ao avanço da ciência, garantindo que todos tenham acesso à saúde hoje e nas próximas gerações. Nossos esforços resultam em mais de 26 milhões de pessoas tratadas com nossos medicamentos e mais de 30 bilhões de testes realizados usando nossos produtos de diagnóstico. Nós nos capacitamos para explorar novas possibilidades, promover a criatividade e manter as nossas ambições altas, para fornecer soluções de saúde que mudem a vida e causem um impacto global.Vamos construir juntos um futuro mais saudável.**A Roche é um empregador que pratica políticas de igualdade de oportunidades.**
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