Cell Culture Operator

vor 1 Woche


Basel, Schweiz Novartis Farmacéutica Vollzeit

Das Cell Bank Center von Basel BDSS ist eine Produktionseinheit (MU), die für die Herstellung von GMP- und analytischen Zellbanken für Novartis Biologics verantwortlich ist.

Der Betreiber ist verantwortlich für den GMP-konformen Herstellungsprozess der Säugetierzellbanking im Basel Cell Bank Center.

Aufgaben
  • Durchführung aller notwendigen Verarbeitungsschritte des Zellbankings mit höchstem Fertigkeitsniveau in aseptischer/niedriger Bioburden-Technik (Auftauen, Zellpassage, Zellzählung und Zellbankeinfrierung)
  • Aseptisches Ankleiden und Arbeiten in Zone C und unter dem Laminar-Flow-Haube für längere Zeiträume.
  • Planung, Vorbereitung (z.B. Verfügbarkeit von Vorräten, Einsatzbereitschaft der Ausrüstung, Reinigung) und eigenständige Durchführung von Operationen (Initiative ergreifen).
  • Wartung und Vorbereitung der Ausrüstung/Umgebung für den Einsatz.
  • Arbeiten mit automatisierten Zellverarbeitungsgeräten wie dem Vial-Füller.
  • Durchführung von In-Prozess-Operationen wie statische Probenahme und In-Prozess-Umgebungsüberwachung.
  • Dokumentation aller Schritte im zugewiesenen Chargenprotokoll gemäß GMP-Anforderungen.
  • Unterstützung bei Abweichungsuntersuchungen und Inspektionen.
  • Ausführung anderer zugewiesener Aufgaben, z.B. Chargenprotokollüberprüfung, Prozessoptimierungen, Sicherheitsbegehungen.
  • Arbeiten mit flüssigem Stickstoff für den Zellbanktransport und die Lagerung.
Fähigkeiten

Sprache: Deutsch: fließend, Englisch: Grundkenntnisse (optional)

Erfahrungen

Zellkultur/Kultivierung, Zellbanking

Technische / Funktionale Fähigkeiten & Kenntnisse

Starke Zusammenarbeit und Teamgeist, Durchführung von Herstellungsprozessen, Allgemeine HSE-Kenntnisse, Kenntnisse von GMP, Grundkenntnisse von IT-Anwendungen und -Tools.

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