PhD on Computational Assessment of Spinal Instability in Scoliosis
vor 19 Stunden
Home » Job Posting » PhD on Computational Assessment of Spinal Instability in Scoliosis
PhD on Computational Assessment of Spinal Instability in ScoliosisAre you eager to understand how instability in the growing spine can lead to excessive tissue strains and whether this could result in scoliosis?
Adolescent Idiopathic Scoliosis (AIS) is a 3D deformity of the spine affecting previously healthy children, substantially reducing their quality of life and creating a life-long burden of disease. Till now, no curative treatment exists partly because its cause and disease mechanism are still unknown. In this ERC funded project, we will uncover whether a complex perfect storm of anatomical, biomechanical and mechanobiological causes in the intervertebral disc are responsible for AIS.
During the adolescent growth spurt, many changes are occurring in our spines. If tissue maturation is not matched by increasing loads and changes in shape, this could lead to spinal instability and excessive tissue strains. Until now this was not possible to study because AIS only occurs in human children and there were no safe methods to image their spines repeatedly during growth. In the ERC project, we are running a clinical study using newly developed MRI-based synthetic CT imaging to collect such information in normal and AIS children.
In this PhD research, we will first develop methods to generate subject-specific FE spine models. These will be based on a combination of landmark recognition, statistical shape/appearance modeling, and machine learning methods. Once validated against imaging and biomechanical data from cadaveric spines, subject-specific multi-scale motion segment and spine models will be generated from the imaging data to explore spinal instability and intervertebral disc deformations during growth in the children of the clinical study.
The PhD candidate will contribute to a multi-disciplinary team of biomedical engineers, imaging scientists, and spine surgeons, from the student to senior level, working on engineering, biological, imaging, and clinical studies. An educational and professional development program is offered to all PhD candidates. You will also be involved in teaching courses, as well as contribute to the supervision of bachelor and master students. Based on your research, you will be expected to present at conferences, publish in scientific journals, and write a doctoral dissertation.
Job requirementsWe are accepting applications from enthusiastic and highly talented candidates who meet the following requirements:
- A MSc degree (or equivalent) in biomedical engineering or a comparable domain.
- Experience and knowledge of tissue biomechanics is appreciated.
- A research-oriented attitude.
- Ability to work in a team and with industrial partners.
- Fluent in spoken and written English.
- We offer a meaningful job in a dynamic, stimulating, and ambitious team environment.
- A full-time employment for four years, with intermediate evaluation after nine months.
- A gross monthly salary and benefits in accordance with the Collective Labor Agreement for Dutch Universities.
- Additionally, an annual holiday allowance of 8% of the yearly salary, plus a year-end allowance of 8.3% of the annual salary.
- A broad package of fringe benefits, including an excellent technical infrastructure, moving expenses, and savings schemes.
- Family-friendly initiatives are in place, such as an international spouse program, and excellent on-campus children day care and sports facilities.
Do you recognize yourself in this profile and would you like to know more? Please contact dr. Bert van Rietbergen (b.v.rietbergen@tue.nl) or prof. Keita Ito (k.ito@tue.nl). Please include a curriculum vitae with a list of your publications.
#J-18808-Ljbffr-
PhD Position in Computational Chemistry Researcher
vor 4 Wochen
Zürich, Zürich, Schweiz University of Zurich Vollzeit**About the Opportunity**The University of Zurich is seeking a highly motivated and skilled PhD researcher to join our team in the field of computational chemistry. The successful candidate will work on the development and application of novel approaches for studying functional catalytic compounds.**Responsibilities and Objectives**Develop and apply advanced...
-
Senior Computational Biologist
vor 1 Monat
Zürich, Zürich, Schweiz Institute of Microbiology VollzeitJob Title: Senior Computational BiologistJob Description:We are seeking a highly skilled Senior Computational Biologist to join our team at the Institute of Microbiology. The ideal candidate will have a strong background in bioinformatics, computational biology, or a related field, with expertise in the analysis and interpretation of omics...
-
Staff Bioinformatician/Computational Biologist
vor 8 Monaten
Zürich, Schweiz Institute of Microbiology VollzeitJob description Data analysis. The candidate supports research projects of PhD students and postdocs at the IMB by applying (and/or advising on) appropriate biostatistics and modelling methods for the analysis, integration and visualization of omics data (e.g., genomics, metagenomics, metatranscriptomics, proteomics, metabolomics). Data...
-
Zürich, Schweiz IT'IS Foundation VollzeitCentral nervous system disorders such as spinal cord injury (SCI) and stroke lead to distinct impairments in motor control and balance. Epidural electrical stimulation (EES) of lumbar and sacral segments of the spinal cord has been proven to restore voluntary and coordinated movements of the lower limbs in various animal models. Translation of this...
-
Senior Director Of Computational Biology
vor 6 Monaten
Zürich, Schweiz Luminary Group VollzeitLuminary Group is seeking a highly skilled and experienced Senior Director of Computational Biology to lead our client's efforts in leveraging computational techniques to extract valuable insights from biological and clinical data. As the Senior Director of Computational Biology, you will play a key role in driving innovation and advancing the field of...
-
Senior Director Of Computational Biology
vor 2 Monaten
Zürich, Schweiz Luminary Group VollzeitLuminary Group is seeking a highly skilled and experienced Senior Director of Computational Biology to lead our client's efforts in leveraging computational techniques to extract valuable insights from biological and clinical data. As the Senior Director of Computational Biology, you will play a key role in driving innovation and advancing the field of...
-
Zürich, Zürich, Schweiz University of Zurich VollzeitOverviewWe are seeking highly motivated postdoctoral researchers to join our team at the University of Zurich in an exciting ERC-funded project focused on computational psychiatry. As a postdoctoral researcher, you will have the opportunity to take a leading role in a cutting-edge international project, working with a diverse and passionate team in Zurich...
-
Open PhD position in computational chemistry
vor 6 Monaten
Zürich, Schweiz University of Zurich VollzeitYour responsibilities The PhD project will deal with development and application of novel, accurate approaches for the study of functional catalytic compounds. A possible direction of the project is the development of advanced dynamic approaches for detailed and realistic study of reaction mechanisms and reaction networks considering in a sophisticated...
-
Computational Neuroscience Modeling Specialist
vor 2 Wochen
Zürich, Zürich, Schweiz Laboratory of Biosensors and Bioelectronics (LBB) VollzeitJob OverviewLaboratory of Biosensors and Bioelectronics (LBB) is seeking a highly skilled Computational Neuroscience Modeling Specialist to join our team. This full-time position offers a competitive salary ranging from $80,000 to $110,000 annually.Job DescriptionTo develop and validate realistic in silico models of biological neuron networks using...
-
Research Scientist in Computational Psychiatry
vor 4 Wochen
Zürich, Zürich, Schweiz University of Zurich VollzeitAbout the PositionWe are seeking a highly motivated Research Scientist to join our team at the University of Zurich. The successful candidate will contribute to an international ERC Synergy project, applying cutting-edge technology to clinically relevant questions in psychiatry.ResponsibilitiesThe candidate will take a leading role in the project, working...
-
ERC-funded PhD position in computational psychiatry
vor 8 Monaten
Zürich, Schweiz University of Zurich VollzeitYour responsibilities The successful candidates will have the chance to work in an exciting and timely international project, together with a motivated and diverse team in Zurich and with investigators over three international sites. In addition, the candidate will have the opportunity to conduct analyses of behavioral and imaging data, disseminate...
-
Lead Computational Biology Researcher
vor 3 Wochen
Zürich, Zürich, Schweiz Luminary Group VollzeitLuminary GroupWe are seeking an experienced and accomplished Senior Director of Computational Biology to spearhead our client's efforts in leveraging computational techniques to extract valuable insights from biological and clinical data.About the Role:This is a highly rewarding opportunity for an expert in computational biology to lead a team of researchers...
-
Zürich, Zürich, Schweiz Department of Health Sciences and Technology VollzeitJob Title: Postdoctoral Researcher for Data Science in Spinal Cord InjuryWe are seeking a highly motivated Postdoctoral Researcher to join our team at the Department of Health Sciences and Technology. The successful candidate will be responsible for leading the implementation, training, and benchmark of state-of-the-art data science pipelines to characterize...
-
Zürich, Zürich, Schweiz University of Zurich VollzeitAbout the PositionThe University of Zurich seeks a highly motivated Postdoctoral Researcher to join our team in the field of population genomics and bioinformatics on language evolution. As a key member of our research group, you will contribute to the analysis of genomic and linguistic data to better understand the evolution of languages.Your...
-
Zürich, Schweiz Biomechanics Summer Course VollzeitHome » Job Posting » Doctoral Position: Musculoskeletal Simulation of Subjects with Lumbar Spinal StenosisDoctoral Position: Musculoskeletal Simulation of Subjects with Lumbar Spinal StenosisThe Institute for Biomechanics (IfB) is dedicated to the biomechanical and mechanobiological study of the human body across all scales, to investigate and characterise...
-
Zürich, Zürich, Schweiz Luminary Group VollzeitSenior Director of Computational BiologyLuminary Group is a leading organization in the field of computational biology, dedicated to leveraging cutting-edge techniques to extract valuable insights from biological and clinical data. We are seeking a highly skilled and experienced Senior Director of Computational Biology to lead our client's efforts in driving...
-
Research Scientist
vor 4 Wochen
Zürich, Zürich, Schweiz University of Zurich VollzeitAbout the OpportunityWe are seeking a highly motivated and talented researcher to join our team as a Research Scientist in Computational Psychiatry at the University of Zurich.Your ResponsibilitiesConduct analyses of behavioral and imaging dataDisseminate study results in peer-reviewed journalsSupervise undergraduate studentsParticipate in ongoing projects...
-
PhD Position in Theoretical Chemistry and Catalysis
vor 2 Wochen
Zürich, Zürich, Schweiz University of Zurich VollzeitCompany OverviewWe are a research group at the University of Zurich, dedicated to advancing our understanding of chemical reactions and their applications. Our team has expertise in theoretical chemistry, catalysis, and computational methods.SalaryThe successful candidate can expect a competitive salary, estimated to be around 58'000 CHF per year,...
-
Zürich, Zürich, Schweiz Department of Health Sciences and Technology VollzeitJob OpportunityThe Department of Health Sciences and Technology at ETH Zurich is seeking a highly motivated Postdoctoral Researcher to join our team in the field of data science for spinal cord injury research.Key ResponsibilitiesFamiliarize yourself with international databases collecting data on SCI patients and lead the implementation, training, and...
-
Zürich, Zürich, Schweiz Department of Health Sciences and Technology VollzeitJob OpportunitiesWe are seeking a highly motivated and skilled Postdoctoral Researcher to join our team in the Department of Health Sciences and Technology at ETH Zurich. The successful candidate will work on a 2-year project-based contract focused on data science and spinal cord injury research.Key ResponsibilitiesFamiliarize yourself with various...
