Director of Quantitative Systems Pharmacology

vor 2 Wochen

Basel, Schweiz LYO-X AG Vollzeit

Change how drugs are developed today for new treatments tomorrow.

We are a team of highly motivated individuals who want to impact how drugs are developed today. If you have great computational skills and dare to use them for tackling the complex biology underlying human diseases: LYO-X is the right place for you.

At LYO-X, you can maximize your individual potential and expertise while pursuing a career that reflects your passions and lifestyle.

Director of Quantitative Systems Pharmacology (QSP) Modeling

We are currently seeking a talented and innovative Director of Quantitative Systems Pharmacology (QSP) Modeling to provide scientific and project leadership in the areas of quantitative systems pharmacology and mechanistic PK/PD modeling projects of different therapeutic modalities. The ideal candidate will manage junior modelers, lead multiple concurrent client projects working closely with client teams to build fit-for-purpose mathematical models that help drive decisions in drug development.

LYO-X is an established Swiss company located in Basel providing consulting and Quantitative Systems Pharmacology modelling services for the preclinical and clinical development of drugs to our customers worldwide. Our customers range from highly innovative biotechnology companies, international large pharmaceutical companies to non-profit health organizations. LYO-X is one of the very few companies globally that is successfully applying Quantitative Systems Pharmacology as a service to help develop the next generation of drugs to bring better medicines to patients faster.

At LYO-X we want our associates to grow and develop both inside and outside of work and we offer a flexible and collaborative working environment, to enable this. LYO-X provides the space to maximize your potential and the opportunity to grow your expertise through exciting and novel project work, interaction with global clients and learning from other experienced colleagues around you.

Required Skills, Abilities and Education:

  • PhD or equivalent in biomedical engineering, chemical engineering, biophysics, mathematics, biology, biochemistry, pharmaceutical sciences or related field.
  • At least 10 years of pharmaceutical or biotech experience in building QSP or mechanistic PK/PD models.
  • Excellent understanding of methodologies and principles of advanced mathematical modeling and simulations.
  • Understanding of pharmacokinetics and pharmacodynamics modeling for preclinical and clinical bio-therapeutics.
  • Understanding of drug discovery and development processes.
  • Expert in differential equations and coding with MATLAB, R and other relevant scientific computing languages.
  • Experience with population PK/PD models, statistical modeling is required.
  • Excellent oral and written communication skills; ability to engage and effectively communicate within a cross-disciplinary team is highly valued.
  • Prior experience as a project team representative on a multifunctional team is required.
  • Experience managing workload and timeline and track record of delivering work on time.
  • Record of scientific achievement through peer-reviewed publications, invited oral presentations, or patents.
  • Passion for data driven analysis, applying innovative quantitative solutions to advance projects.

If you are interested and would like to contribute to the growth of LYO-X, we would be pleased to receive your application including a letter of application, curriculum vitae, academic transcripts and job references. Please send your application to hiring@lyo-x.com.

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