Postdoc function of cytokines in regulating mammalian hematopoietic stem and progenitor cell fates
vor 2 Wochen
ETH Zürich is well known for its excellent education, ground-breaking fundamental research and for implementing its results directly into practice.
The Cell Systems Dynamics group studies cell fate choices and their molecular control in complex and dynamic mammalian cell systems.
In the project advertised here, we are interested in the function of cytokines in regulating mammalian hematopoietic stem and progenitor cell fates.
We will use a combination of stem cell purification, culture and manipulation, long-term live cell imaging, single cell tracking and quantification, large volume 3D bone marrow imaging with single molecule sensitivity, and AI-supported computational analysis.
We are seeking a highly motivated postdoc with expertise in molecular and cellular biology, mammalian blood stem and progenitor cell purification, culture and manipulation, and advanced imaging to join our interdisciplinary team.
Key Responsibilities:- Quantitative in situ and in vitro imaging studies related to cytokine signaling and cell-cell interactions.
- Design and optimization of multiplexed fluorescence imaging, in situ single-molecule detection, and 3D immunofluorescence techniques.
- Primary human and mouse stem cell cultures and lentiviral manipulations to study hematopoietic stem cell dynamics.
- Primary mammalian tissue handling: isolation, fixation and vibratome sectioning for immunostaining.
- AI-assisted image analysis for spatial analysis of tissue samples.
- Multidisciplinary teamwork, with immunologists, data scientists, and bioengineers, to integrate imaging-based techniques into immunotherapy development.
- Presentation and publication of research findings.
- Supervision of junior researchers to provide technical and scientific training in advanced imaging and molecular techniques.
- Contribution to undergraduate student teaching.
Required Qualifications:
- Ph.D. in Biotechnology, Immunology, Molecular Biology, Stem Cell Biology or a related field.
- Published expertise in:
- mammalian hematopoietic stem cell biology, purification, culture and manipulation.
- molecular biology.
- lenti virus cloning and production.
- live-cell biosensor cloning and use for quantification of cytokine signaling dynamics.
- long-term fluorescence live-cell imaging, single cell tracking and quantification.
- large volume multi-color 3D imaging.
- quantitative computational image analysis.
- Your career with impact: Become part of ETH Zurich, which not only supports your professional development, but also actively contributes to positive change in society.
In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected.
Curious? So are we.We look forward to receiving your online application with the following documents:
- CV including information on the required qualifications listed above
Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.
Further information about the Department of Biosystems Science and Engineering can be found on our website www.webseite.ethz.ch. Questions regarding the position should be directed to Prof. Timm Schroeder, email timm.schroeder@bsse.ethz.ch (no applications).
ETH Zurich is one of the world's leading universities specializing in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society.
#J-18808-Ljbffr-
Zürich, Zürich, Schweiz Karlstad University VollzeitPostdoc function of cytokines in regulating mammalian hematopoietic stem and progenitor cell fatesETH Zürich is well known for its excellent education, ground-breaking fundamental research and for implementing its results directly into practice.The Cell Systems Dynamics group studies cell fate choices and their molecular control in complex and dynamic...
-
Oils and Fats Category Lead
Vor 2 Tagen
Zürich, Zürich, Schweiz Aston Carter VollzeitAston Carter is seeking a highly motivated Procurement Professional with Market Expertise to join their team. The successful candidate will be responsible for leading the procurement activities for oils and fats category.About the RoleResponsible for all buying activities across the oils and fats category.Determine independently spend allocation up to or...
-
Director of Functions and Banquets
Vor 2 Tagen
Zürich, Zürich, Schweiz Mandarin Oriental Hotel Group Limited VollzeitWe are seeking an experienced and dynamic individual to join our team as a Director of Functions and Banquets. As a key member of our events team, you will play a vital role in ensuring the success of our banquets and events.Your Key Responsibilities:Strategic planning and operational management of the banquet department.Developing and implementing...
-
Zürich, Zürich, Schweiz ETH get hired VollzeitPostdoc Position at the Chair of Strategic Management and Innovation (SMI) at ETH Zurich100 %The Chair of Strategic Management and Innovation at ETH Zurich's Department of Management, Technology, and Economics, under the leadership of Prof. Dr. Georg von Krogh, invites applications for a Postdoc position. This position offers a unique opportunity to engage...
-
Brain Function Analyst
Vor 4 Tagen
Zürich, Zürich, Schweiz University of Zurich VollzeitWe are looking for an enthusiastic and dedicated PhD candidate to join our team at the University Hospital Zurich. The candidate will be responsible for conducting two randomized-controlled trials to further validate the pilot study on driving-simulation-based maintenance of wakefulness test (DS-MWT) in obstructive sleep apnea syndrome (OSAS)-affected...
-
Zürich, Zürich, Schweiz University of Zurich VollzeitYour responsibilities You explore the cell biology of various cell death pathways (apoptosis, pyroptosis, necroptosis, ferroptosis) and their potential to eradicate resistant disease in the context of acute leukemia of childhood. You dissect the relationship between intrinsic and extrinsic signaling programs using a representative xenograft bank of...
-
Zürich, Zürich, Schweiz University of Zurich VollzeitYour responsibilities The Dynamic and Distributed Information Systems Group at the University of Zurich is looking for motivated applicants who are interested in conducting research at the intersection of computer science and AI/NLP. We are seeking applicants who have experience with large language models, large and multi-modal data processing,...
-
Scientist - Protein Engineering and Development
Vor 7 Tagen
Zürich, Zürich, Schweiz Karlstad University VollzeitThe position of Scientist – Antibody & Nanobody Drug Discovery at ETH Zurich offers a unique opportunity for a highly skilled scientist to contribute to the development of innovative therapeutics. As a member of our interdisciplinary team, you will be responsible for advancing novel protein binders through various stages of development, from initial...
-
Cell Biology and Technology Professional
Vor 4 Tagen
Zürich, Zürich, Schweiz EPM Scientific VollzeitEPM Scientific is a Swiss life science startup focused on developing innovative, patient-specific, and clinically relevant drug sensitivity testing technologies.Our mission is to improve disease management and optimize treatment outcomes for healthcare professionals through collaborative partnerships with pharmaceutical research companies.We are currently...
-
Head of Human Resources and Corporate Functions
Vor 2 Tagen
Zürich, Zürich, Schweiz La Prairie Group AG VollzeitLa Prairie Group AG, a leading luxury skincare company, seeks an experienced HR professional to drive business results through strategic HR initiatives. As the Head of Human Resources and Corporate Functions, you will serve as a trusted advisor to management and employees, ensuring that HR processes and strategies align with the company's goals.Key...
-
Cell Culture Expert Oncology
vor 3 Stunden
Zürich, Zürich, Schweiz F. Hoffmann-La Roche Gruppe VollzeitRarely do organizations have the opportunity to combine cutting-edge science with passionate individuals who share their vision. At Roche, we strive to foster an environment where everyone feels valued and empowered to push the boundaries of what is possible.About the JobWe are seeking an Immunotherapy Laboratory Technician to join our dedicated team in the...
-
Zürich, Zürich, Schweiz ETH VollzeitJob description This is a fixed term 3-years postdoc position with a possible start after July 1st . The project will involve high-pressure and high temperature experimental work using a laser-heated or externally-heated diamond anvil cell combined with various laser spectroscopic methods (Raman, Brillouin scattering) and synchrotron X-rays to...
-
PhD Student in Cell Biology Wanted
Vor 4 Tagen
Zürich, Zürich, Schweiz Institute of Molecular Biology & Biophysics, ETH Zurich VollzeitJob DescriptionThis PhD position involves researching the regulation of microtubules by protein complexes.The ideal candidate will have a strong background in molecular biology, cell culture, and protein purification methods.Key ResponsibilitiesConduct experiments to investigate microtubule regulationDevelop and implement new methods for studying microtubule...
-
PostDoc in Neuropsychiatry and Biomarkers
vor 1 Woche
Zürich, Zürich, Schweiz University of Zurich VollzeitYour responsibilities The successful candidate will take a leading role in statistical and methodological approaches as well as substantially contribute to the scientific output of the group by publishing in peer-reviewed journals and by presenting results at international conferences. Additionally, the candidate will supervise graduate and master...
-
Zürich, Zürich, Schweiz Maserati of San Diego VollzeitHome PhD PhD Position in Microstructure of Cellulose, Zurich, Switzerland PhD Position in Microstructure of Cellulose: We are excited to offer a fully funded PhD position, focused on an interdisciplinary project that integrates soft matter physics and material science to develop the next generation of architected bacterial cellulose for fundamental...
-
Research Scientist
Vor 7 Tagen
Zürich, Zürich, Schweiz Karlstad University VollzeitThe position of Scientist – Antibody & Nanobody Drug Discovery at ETH Zurich is an excellent opportunity for a visionary researcher to join our team and drive the development of innovative therapeutics.This role requires a strong background in biotechnology, molecular biology, or related fields, with hands-on experience in workflows and protocols relevant...
-
Research Fellow in Psychology and Education
Vor 4 Tagen
Zürich, Zürich, Schweiz University of Zurich Vollzeit**Job Overview**Postdoctoral Researcher in Educational Science NeededWe are seeking a highly qualified Postdoctoral Researcher to join our team at the University of Zurich. As a postdoc, you will be responsible for advancing our research agenda in education science.Main Responsibilities:Conduct independent research and contribute to collaborative...
-
Buyer
vor 1 Woche
Zürich, Zürich, Schweiz Aston Carter VollzeitJoin Our Team as a Buyer (Oils and Fats)We are seeking a highly skilled and motivated Buyer specializing in oils and fats to join our team at one of the largest food manufacturing companies in the world. This is an exciting opportunity to be part of a dynamic and innovative organization.Responsibilities:Be fully responsible for a smooth, reliable procurement...
-
Master Production Planner
Vor 2 Tagen
Zürich, Zürich, Schweiz Johnson and Johnson VollzeitAt Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across...
-
Valuation Function Head
Vor 2 Tagen
Zürich, Zürich, Schweiz Apollo Solutions VollzeitApollo Solutions is a global Internal Audit and IT Audit Headhunter, working closely with clients to find top talent. We have partnered with a Global Conglomerate in the Financial Services space to build a new department and hire a Director of Asset Valuations.ResponsibilitiesThe successful candidate will:Develop and manage the valuation function, overseeing...