Lead Chemical Process R&D Scientist
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Lead Chemical Process R&D Scientist (m/f/d)
For a leading pharmaceutical company, we are looking for a qualified
Lead Chemical Process R&D Scientist (m/f/d)
General Information:
- Location: Basel
- Workload: 100%
- Start: ASAP
- Duration: 12 months (extension possible)
- Home Office: up to 40%
- Travel: Occasional travel (up to 4 trips per year) to CDMOs in Europe or Asia
Your Responsibilities:
- Lead chemical process research and development activities for clinical-stage pharmaceutical projects, with a strong focus on late-stage development and process optimization.
- Manage and guide internal process chemistry teams of up to five scientists and associates in a matrix leadership role.
- Oversee external development and manufacturing activities at CDMOs, ensuring alignment with project objectives, timelines, quality standards, and budget expectations.
- Drive synthetic route scouting, process optimization, process understanding, scale-up activities, and delivery of drug substance material.
- Coordinate internal and external stakeholders to ensure timely, safe, and cost-effective supply of APIs and advanced intermediates.
- Lead technology transfer activities from development to manufacturing environments.
- Ensure all activities comply with safety, quality, regulatory, and sustainability requirements.
- Utilize scientific expertise and data-driven approaches to support process development decisions and project strategy.
- Contribute to project planning, risk assessment, technical documentation, and cross-functional decision-making.
Your Profile:
- PhD or Postdoctoral qualification in Synthetic Organic Chemistry.
- Minimum 5 years of pharmaceutical chemical process R&D experience, with demonstrated expertise in late-stage process development and scale-up.
- Proven track record of leading scientific teams and driving project deliverables within process chemistry organizations.
- Strong experience managing external development, technology transfer, and manufacturing activities at CDMOs.
- Deep understanding of synthetic organic chemistry, process optimization, scale-up principles, and manufacturing support.
- Proficient in chemistry-related software and tools, including chemical drawing programs, literature and patent search platforms, Design of Experiments (DoE) applications, analytical software, and project management tools.
- Experience with kinetic modelling and process simulation software is considered an advantage.
- Familiarity with GMP environments and pharmaceutical development processes is a plus.
- Strong organizational, communication, and stakeholder management skills.
- Fluent English is mandatory; German language skills are advantageous.
Please note: Only CVs in English can be accepted and submitted for this role.
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