Principal Scientist Cmc Analytics

vor 2 Wochen


Zürich, Zürich, Schweiz SwisSolution Human Capital AG Vollzeit
Are you looking forward to join a highly motivated CMC team and to support all product development & manufacturing programs? Then keep reading

Our client is biotech company specialized in the development of glycoengineered biologics near Zurich.

Tasks

  • Based on the analytical control strategy define in/ outsourcing concepts between GlycoEra, CRO's and CMO's
  • Ensure capacity sourcing to reach goals according to plans
  • Planning and execution of early formulation and stability studies based on established stability indicating assays
  • Phase appropriate validation of analytical methods
  • Analyzing biomolecules such as proteins and glycans (e.g., by U/HPLC, SEC, IEX, mass spectrometry, immunoassays)
  • Technology transfer to and oversight of CMOs and CROs tasked with analysis of GlycoEra molecules for product characterization and GMP release testing
  • Independently planning and executing analytical research projects
  • Maintaining analytical instruments
  • Processing, evaluating, and reporting of data as well as presentation in scientific meetings

Requirements:

  • PhD in Natural Sciences or Analytical Sciences
  • 10+ years 'working experience in the biotech and/or pharma industry
  • Minimum 5 years of relevant analytical/ QC industry experience with GMP exposure
  • Broad Experience and knowledge in protein biochemistry and protein analytics, including post translational modifications such as glycosylation
  • Handson experience in analytical method validation, technology transfer and CMC regulatory analytical matters
  • Proven experience in chromatographic analysis of biological molecules including proteins and peptides is a must
  • Practical experience with mass spectrometry and data evaluation
  • Handson experience working with and maintaining HPLC/UPLC instruments
  • Experience in statistical data evaluation and high affinity for software tools
  • Wellconnected in the analytical technology and instrumentation community
  • Good ITknowledge (Excel, PowerPoint, databases)
  • Very good communication skills in English, written and verbal
  • Excellent planning and strong organizational skills, able to manage multiple tasks simultaneously and set priorities
  • Proactive and problemsolving attitude
  • Personal resilience, perseverance, energy and drive
  • Excellent conceptual and scientific thinking to approach and solve complex issues and their implications
  • Selfmotivation and ability to work independently in a fastpace, small company environment
  • Excellent interpersonal and negotiation skills
  • Team player, collaborative attitude.

Benefits:

  • Startup culture
  • 5 weeks vacation
- well located office
- career opportunities

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